RNF139 protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DERL1	ERLEC1	ENSPTRP00000035139	ENSPTRP00000091483	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	XTP3-transactivated gene B protein.	0.903
DERL1	HM13	ENSPTRP00000035139	ENSPTRP00000087015	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Histocompatibility minor 13.	0.710
DERL1	HM13-2	ENSPTRP00000035139	ENSPTRP00000086340	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Histocompatibility (Minor) 13.	0.710
DERL1	OS9	ENSPTRP00000035139	ENSPTRP00000082230	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Osteosarcoma amplified 9, endoplasmic reticulum lectin.	0.917
DERL1	RNF139	ENSPTRP00000035139	ENSPTRP00000035174	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ring finger protein 139.	0.745
DERL1	SEL1L	ENSPTRP00000035139	ENSPTRP00000011221	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.987
DERL1	VCP	ENSPTRP00000035139	ENSPTRP00000035748	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.994
ERLEC1	DERL1	ENSPTRP00000091483	ENSPTRP00000035139	XTP3-transactivated gene B protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.903
ERLEC1	OS9	ENSPTRP00000091483	ENSPTRP00000082230	XTP3-transactivated gene B protein.	Osteosarcoma amplified 9, endoplasmic reticulum lectin.	0.920
ERLEC1	RNF139	ENSPTRP00000091483	ENSPTRP00000035174	XTP3-transactivated gene B protein.	Ring finger protein 139.	0.676
ERLEC1	SEL1L	ENSPTRP00000091483	ENSPTRP00000011221	XTP3-transactivated gene B protein.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.985
ERLEC1	VCP	ENSPTRP00000091483	ENSPTRP00000035748	XTP3-transactivated gene B protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.813
HM13	DERL1	ENSPTRP00000087015	ENSPTRP00000035139	Histocompatibility minor 13.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.710
HM13	RNF139	ENSPTRP00000087015	ENSPTRP00000035174	Histocompatibility minor 13.	Ring finger protein 139.	0.801
HM13-2	DERL1	ENSPTRP00000086340	ENSPTRP00000035139	Histocompatibility (Minor) 13.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.710
HM13-2	RNF139	ENSPTRP00000086340	ENSPTRP00000035174	Histocompatibility (Minor) 13.	Ring finger protein 139.	0.801
INSIG1	INSIG2	ENSPTRP00000034091	ENSPTRP00000021225	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.917
INSIG1	RNF139	ENSPTRP00000034091	ENSPTRP00000035174	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Ring finger protein 139.	0.782
INSIG1	VCP	ENSPTRP00000034091	ENSPTRP00000035748	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.832
INSIG2	INSIG1	ENSPTRP00000021225	ENSPTRP00000034091	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.917