STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
LYNX1Ly-6/neurotoxin-like protein 1; Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). The proposed role as modulator of nAChR activity seems to be dependent on the nAChR subtype and stoichiometry, and to involve an effect on nAChR trafficking and its cell surface expression, and on single channel properties of the nAChR inserted in the plasma membrane.Modulates functional properties of nicotinic acetylcholine receptors (nAChRs) to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and ex [...] (116 aa)    
Predicted Functional Partners:
SLURP1
Secreted LY6/PLAUR domain containing 1.
      
 0.911
LY6H
Lymphocyte antigen 6 family member H.
      
 0.884
LYPD6
LY6/PLAUR domain containing 6.
      
 0.812
GPIHBP1
Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1.
  
   
 0.743
LY6K
Lymphocyte antigen 6 family member K.
      
 0.706
LYPD2
LY6/PLAUR domain containing 2.
      
 0.574
PLAUR
Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity).
      
 0.529
BCL11A
BAF chromatin remodeling complex subunit BCL11A.
      
 0.519
CHRNA1
Cholinergic receptor, nicotinic, alpha 1 (Muscle).
    
 
 0.495
CHRNB2
CHRNB2 isoform 2.
    
 
 0.491
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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