STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLECPLEC isoform 2. (4684 aa)    
Predicted Functional Partners:
ITGB4
Integrin beta.
  
 0.997
DST
DST isoform 9.
     
0.978
COL17A1
COL17A1 isoform 2.
   
 0.920
SYNE3
Spectrin repeat containing nuclear envelope family member 3.
    
 0.911
CD151
Tetraspanin.
   
 
 0.857
VIM
Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
    
 0.789
PARP10
Poly [ADP-ribose] polymerase 10 isoform X1.
 
    
 0.761
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
   
 0.751
JUP
Junction plakoglobin.
   
 0.733
SPTAN1
SPTAN1 isoform 9.
   
 0.724
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.