STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK2Tyrosine-protein kinase. (1143 aa)    
Predicted Functional Partners:
EPOR
Erythropoietin receptor; Receptor for erythropoietin.
    
 0.998
STAT3
Signal transducer and activator of transcription.
   
 0.995
GHR
Growth hormone receptor.
    
 0.993
SOCS3
Suppressor of cytokine signaling 3.
   
 0.991
CSF2RB
Colony stimulating factor 2 receptor, beta, low-affinity (Granulocyte-macrophage).
   
 0.989
SOCS1
Suppressor of cytokine signaling 1.
   
 0.987
STAT1
Signal transducer and activator of transcription.
   
 0.984
JAK1
Tyrosine-protein kinase.
   
0.980
LEPR
Leptin receptor.
    
 0.980
IFNGR2
Interferon gamma receptor 2.
   
 0.978
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.