STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDCD1LG2Programmed cell death 1 ligand 2. (288 aa)    
Predicted Functional Partners:
PDCD1
Programmed cell death 1.
   
 0.998
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
   
 
 0.924
CD80
CD80 isoform 1.
   
 0.862
HAVCR2
Hepatitis A virus cellular receptor 2.
     
 0.838
CD86
CD86 isoform 3.
   
  
 0.806
ICOS
Inducible T cell costimulator.
   
  
 0.804
CD28
CD28 isoform 3.
   
 
 0.794
B4GAT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1.
      
 0.762
LAG3
LAG3 isoform 3.
     
 0.730
TIGIT
TIGIT isoform 1.
      
 0.718
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.