| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BMI1 | CCND1 | ENSPTRP00000079472 | ENSPTRP00000086048 | BMI1 isoform 1. | CCND1 isoform 1; Belongs to the cyclin family. | 0.449 |
| BMI1 | CDKN2A | ENSPTRP00000079472 | ENSPTRP00000076891 | BMI1 isoform 1. | Cyclin-dependent kinase inhibitor 2A (Melanoma, p16, inhibits CDK4). | 0.570 |
| BMI1 | CDKN2B | ENSPTRP00000079472 | ENSPTRP00000082876 | BMI1 isoform 1. | Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). | 0.500 |
| BMI1 | TP53 | ENSPTRP00000079472 | ENSPTRP00000014836 | BMI1 isoform 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.834 |
| CCND1 | BMI1 | ENSPTRP00000086048 | ENSPTRP00000079472 | CCND1 isoform 1; Belongs to the cyclin family. | BMI1 isoform 1. | 0.449 |
| CCND1 | CDK4 | ENSPTRP00000086048 | ENSPTRP00000039845 | CCND1 isoform 1; Belongs to the cyclin family. | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | 0.999 |
| CCND1 | CDK6 | ENSPTRP00000086048 | ENSPTRP00000033192 | CCND1 isoform 1; Belongs to the cyclin family. | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | 0.999 |
| CCND1 | CDKN1A | ENSPTRP00000086048 | ENSPTRP00000060292 | CCND1 isoform 1; Belongs to the cyclin family. | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | 0.998 |
| CCND1 | CDKN2A | ENSPTRP00000086048 | ENSPTRP00000076891 | CCND1 isoform 1; Belongs to the cyclin family. | Cyclin-dependent kinase inhibitor 2A (Melanoma, p16, inhibits CDK4). | 0.583 |
| CCND1 | CDKN2B | ENSPTRP00000086048 | ENSPTRP00000082876 | CCND1 isoform 1; Belongs to the cyclin family. | Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). | 0.992 |
| CCND1 | TP53 | ENSPTRP00000086048 | ENSPTRP00000014836 | CCND1 isoform 1; Belongs to the cyclin family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.893 |
| CDK4 | CCND1 | ENSPTRP00000039845 | ENSPTRP00000086048 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | CCND1 isoform 1; Belongs to the cyclin family. | 0.999 |
| CDK4 | CDK6 | ENSPTRP00000039845 | ENSPTRP00000033192 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | 0.997 |
| CDK4 | CDKN1A | ENSPTRP00000039845 | ENSPTRP00000060292 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | 0.997 |
| CDK4 | CDKN2A | ENSPTRP00000039845 | ENSPTRP00000076891 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase inhibitor 2A (Melanoma, p16, inhibits CDK4). | 0.642 |
| CDK4 | CDKN2B | ENSPTRP00000039845 | ENSPTRP00000082876 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). | 0.998 |
| CDK4 | MDM2 | ENSPTRP00000039845 | ENSPTRP00000062868 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.667 |
| CDK4 | MDM4 | ENSPTRP00000039845 | ENSPTRP00000051283 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. | 0.583 |
| CDK4 | TP53 | ENSPTRP00000039845 | ENSPTRP00000014836 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.956 |
| CDK6 | CCND1 | ENSPTRP00000033192 | ENSPTRP00000086048 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. | CCND1 isoform 1; Belongs to the cyclin family. | 0.999 |
