VCP protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DERL1	ENSPTRP00000061322	ENSPTRP00000035139	ENSPTRP00000061322	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	annotation not available	0.779
DERL1	NPLOC4	ENSPTRP00000035139	ENSPTRP00000068574	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NPL4 homolog, ubiquitin recognition factor.	0.807
DERL1	NSFL1C	ENSPTRP00000035139	ENSPTRP00000077674	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NSFL1 (P97) cofactor (P47).	0.630
DERL1	SVIP	ENSPTRP00000035139	ENSPTRP00000038843	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Small VCP/p97-interacting protein.	0.742
DERL1	UBXN1	ENSPTRP00000035139	ENSPTRP00000006496	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain protein 1.	0.955
DERL1	UBXN2A	ENSPTRP00000035139	ENSPTRP00000020106	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain protein 2A.	0.544
DERL1	UBXN4	ENSPTRP00000035139	ENSPTRP00000042043	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain-containing protein 2.	0.401
DERL1	UFD1	ENSPTRP00000035139	ENSPTRP00000065513	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin recognition factor in ER associated degradation 1.	0.779
DERL1	VCP	ENSPTRP00000035139	ENSPTRP00000035748	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.994
ENSPTRP00000061322	DERL1	ENSPTRP00000061322	ENSPTRP00000035139	annotation not available	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.779
ENSPTRP00000061322	NPLOC4	ENSPTRP00000061322	ENSPTRP00000068574	annotation not available	NPL4 homolog, ubiquitin recognition factor.	0.989
ENSPTRP00000061322	NSFL1C	ENSPTRP00000061322	ENSPTRP00000077674	annotation not available	NSFL1 (P97) cofactor (P47).	0.791
ENSPTRP00000061322	UBXN1	ENSPTRP00000061322	ENSPTRP00000006496	annotation not available	UBX domain protein 1.	0.886
ENSPTRP00000061322	UBXN2A	ENSPTRP00000061322	ENSPTRP00000020106	annotation not available	UBX domain protein 2A.	0.588
ENSPTRP00000061322	UBXN6	ENSPTRP00000061322	ENSPTRP00000017528	annotation not available	UBX domain protein 6.	0.697
ENSPTRP00000061322	UFD1	ENSPTRP00000061322	ENSPTRP00000065513	annotation not available	Ubiquitin recognition factor in ER associated degradation 1.	0.900
ENSPTRP00000061322	VCP	ENSPTRP00000061322	ENSPTRP00000035748	annotation not available	Valosin containing protein; Belongs to the AAA ATPase family.	0.994
NPLOC4	DERL1	ENSPTRP00000068574	ENSPTRP00000035139	NPL4 homolog, ubiquitin recognition factor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.807
NPLOC4	ENSPTRP00000061322	ENSPTRP00000068574	ENSPTRP00000061322	NPL4 homolog, ubiquitin recognition factor.	annotation not available	0.989
NPLOC4	NSFL1C	ENSPTRP00000068574	ENSPTRP00000077674	NPL4 homolog, ubiquitin recognition factor.	NSFL1 (P97) cofactor (P47).	0.887