ALDH1A1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ALDH1A1

Aldehyde dehydrogenase 1 family, member A1; Belongs to the aldehyde dehydrogenase family. (532 aa)

Predicted Functional Partners:

ADH1A

0.977

AOX1

0.977

ADH4

0.973

ADH1B

0.972

ADH7

0.967

ADH6

0.965

RDH12

0.958

ADH5

0.958

CYP26A1

0.952

CYP26B1

0.951

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADH1A	ADH1B	ENSPTRP00000028008	ENSPTRP00000071388	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	0.973
ADH1A	ADH6	ENSPTRP00000028008	ENSPTRP00000028007	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Alcohol dehydrogenase 6 (class V).	0.450
ADH1A	ALDH1A1	ENSPTRP00000028008	ENSPTRP00000071341	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Aldehyde dehydrogenase 1 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.977
ADH1A	AOX1	ENSPTRP00000028008	ENSPTRP00000048899	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Aldehyde oxidase 1.	0.917
ADH1A	CYP26A1	ENSPTRP00000028008	ENSPTRP00000044339	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	0.924
ADH1B	ADH1A	ENSPTRP00000071388	ENSPTRP00000028008	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	0.973
ADH1B	ADH6	ENSPTRP00000071388	ENSPTRP00000028007	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Alcohol dehydrogenase 6 (class V).	0.466
ADH1B	ALDH1A1	ENSPTRP00000071388	ENSPTRP00000071341	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Aldehyde dehydrogenase 1 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.972
ADH1B	AOX1	ENSPTRP00000071388	ENSPTRP00000048899	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Aldehyde oxidase 1.	0.922
ADH1B	CYP26A1	ENSPTRP00000071388	ENSPTRP00000044339	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	0.909
ADH4	ADH6	ENSPTRP00000069873	ENSPTRP00000028007	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Alcohol dehydrogenase 6 (class V).	0.511
ADH4	ALDH1A1	ENSPTRP00000069873	ENSPTRP00000071341	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldehyde dehydrogenase 1 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.973
ADH4	AOX1	ENSPTRP00000069873	ENSPTRP00000048899	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldehyde oxidase 1.	0.914
ADH4	CYP26A1	ENSPTRP00000069873	ENSPTRP00000044339	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	0.917
ADH5	ALDH1A1	ENSPTRP00000028003	ENSPTRP00000071341	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Aldehyde dehydrogenase 1 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.958
ADH5	AOX1	ENSPTRP00000028003	ENSPTRP00000048899	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Aldehyde oxidase 1.	0.911
ADH5	CYP26A1	ENSPTRP00000028003	ENSPTRP00000044339	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	0.928
ADH6	ADH1A	ENSPTRP00000028007	ENSPTRP00000028008	Alcohol dehydrogenase 6 (class V).	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	0.450
ADH6	ADH1B	ENSPTRP00000028007	ENSPTRP00000071388	Alcohol dehydrogenase 6 (class V).	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	0.466
ADH6	ADH4	ENSPTRP00000028007	ENSPTRP00000069873	Alcohol dehydrogenase 6 (class V).	Alcohol dehydrogenase 4 (class II), pi polypeptide.	0.511