MAFA protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

MAFA

MAF bZIP transcription factor A. (348 aa)

Predicted Functional Partners:

PDX1

0.839

INS

0.820

NFE2

0.603

BACH2

0.603

NFE2L2

0.603

FOS

0.601

NEUROG3

0.597

SLC2A2

0.591

NFE2L1

0.584

MAP4K4

0.577

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BACH2	FOS	ENSPTRP00000031473	ENSPTRP00000078496	BACH2 isoform 1.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.499
BACH2	MAFA	ENSPTRP00000031473	ENSPTRP00000036387	BACH2 isoform 1.	MAF bZIP transcription factor A.	0.603
FOS	BACH2	ENSPTRP00000078496	ENSPTRP00000031473	Fos proto-oncogene, AP-1 transcription factor subunit.	BACH2 isoform 1.	0.499
FOS	INS	ENSPTRP00000078496	ENSPTRP00000077843	Fos proto-oncogene, AP-1 transcription factor subunit.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.497
FOS	MAFA	ENSPTRP00000078496	ENSPTRP00000036387	Fos proto-oncogene, AP-1 transcription factor subunit.	MAF bZIP transcription factor A.	0.601
FOS	NFE2	ENSPTRP00000078496	ENSPTRP00000008572	Fos proto-oncogene, AP-1 transcription factor subunit.	Nuclear factor, erythroid 2.	0.519
FOS	NFE2L2	ENSPTRP00000078496	ENSPTRP00000064585	Fos proto-oncogene, AP-1 transcription factor subunit.	Nuclear factor (Erythroid-derived 2)-like 2.	0.560
INS	FOS	ENSPTRP00000077843	ENSPTRP00000078496	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.497
INS	MAFA	ENSPTRP00000077843	ENSPTRP00000036387	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MAF bZIP transcription factor A.	0.820
INS	NEUROG3	ENSPTRP00000077843	ENSPTRP00000060199	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NEUROG3 isoform 1.	0.585
INS	NFE2L2	ENSPTRP00000077843	ENSPTRP00000064585	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Nuclear factor (Erythroid-derived 2)-like 2.	0.425
INS	PDX1	ENSPTRP00000077843	ENSPTRP00000009769	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Pancreas/duodenum homeobox protein 1; Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element [...]	0.851
INS	SLC2A2	ENSPTRP00000077843	ENSPTRP00000026876	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.674
MAFA	BACH2	ENSPTRP00000036387	ENSPTRP00000031473	MAF bZIP transcription factor A.	BACH2 isoform 1.	0.603
MAFA	FOS	ENSPTRP00000036387	ENSPTRP00000078496	MAF bZIP transcription factor A.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.601
MAFA	INS	ENSPTRP00000036387	ENSPTRP00000077843	MAF bZIP transcription factor A.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.820
MAFA	MAP4K4	ENSPTRP00000036387	ENSPTRP00000079776	MAF bZIP transcription factor A.	MAP4K4 isoform 6.	0.577
MAFA	NEUROG3	ENSPTRP00000036387	ENSPTRP00000060199	MAF bZIP transcription factor A.	NEUROG3 isoform 1.	0.597
MAFA	NFE2	ENSPTRP00000036387	ENSPTRP00000008572	MAF bZIP transcription factor A.	Nuclear factor, erythroid 2.	0.603
MAFA	NFE2L1	ENSPTRP00000036387	ENSPTRP00000046646	MAF bZIP transcription factor A.	Nuclear factor (Erythroid-derived 2)-like 1.	0.584