STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OFD1OFD1 centriole and centriolar satellite protein. (1012 aa)    
Predicted Functional Partners:
SDCCAG8
Serologically defined colon cancer antigen 8.
    
 
 0.905
PLK1
Serine/threonine-protein kinase PLK.
   
 0.894
PCM1
Pericentriolar material 1.
   
 
 0.836
C8H8orf37
Chromosome 8 open reading frame 37.
      
 0.831
NDE1
NudE nuclear distribution gene E homolog 1.
    
 
 0.808
FOPNL
FOPNL isoform 8.
   
 
 0.784
CCDC14
CCDC14 isoform 12.
   
 
 0.778
TULP1
Tubby-like protein; Belongs to the TUB family.
    
 
 0.750
CEP290
CEP290 isoform 5.
    
 
 0.723
ARL13B
ADP ribosylation factor like GTPase 13B.
   
 
 0.716
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.