CFP protein (Pan troglodytes) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

CFP

Complement factor properdin. (469 aa)

Predicted Functional Partners:

C3

0.999

C2

0.915

B3GLCT

0.724

NCR1

0.701

ENSPTRP00000087608

0.701

MBL2

0.695

LOC462577

0.668

LOC100616513

0.668

LOC462577-2

0.668

C1S

0.665

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GLCT	CFP	ENSPTRP00000009803	ENSPTRP00000037513	Beta 1,3-galactosyltransferase-like.	Complement factor properdin.	0.724
C1S	C2	ENSPTRP00000054795	ENSPTRP00000076687	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	0.490
C1S	C3	ENSPTRP00000054795	ENSPTRP00000017648	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	Complement component 3.	0.810
C1S	CFP	ENSPTRP00000054795	ENSPTRP00000037513	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	Complement factor properdin.	0.665
C1S	LOC100616513	ENSPTRP00000054795	ENSPTRP00000064762	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	Complement C4-A-like.	0.713
C1S	LOC462577	ENSPTRP00000054795	ENSPTRP00000064661	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	C4B isoform 1.	0.970
C1S	LOC462577-2	ENSPTRP00000054795	ENSPTRP00000067300	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	Complement C4-A.	0.713
C1S	MBL2	ENSPTRP00000054795	ENSPTRP00000066109	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).	0.845
C2	C1S	ENSPTRP00000076687	ENSPTRP00000054795	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	0.490
C2	C3	ENSPTRP00000076687	ENSPTRP00000017648	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	Complement component 3.	0.996
C2	CFP	ENSPTRP00000076687	ENSPTRP00000037513	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	Complement factor properdin.	0.915
C2	LOC100616513	ENSPTRP00000076687	ENSPTRP00000064762	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	Complement C4-A-like.	0.761
C2	LOC462577	ENSPTRP00000076687	ENSPTRP00000064661	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	C4B isoform 1.	0.761
C2	LOC462577-2	ENSPTRP00000076687	ENSPTRP00000067300	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	Complement C4-A.	0.761
C2	MBL2	ENSPTRP00000076687	ENSPTRP00000066109	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).	0.524
C3	C1S	ENSPTRP00000017648	ENSPTRP00000054795	Complement component 3.	Complement component 1, s subcomponent; Belongs to the peptidase S1 family.	0.810
C3	C2	ENSPTRP00000017648	ENSPTRP00000076687	Complement component 3.	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	0.996
C3	CFP	ENSPTRP00000017648	ENSPTRP00000037513	Complement component 3.	Complement factor properdin.	0.999
C3	LOC100616513	ENSPTRP00000017648	ENSPTRP00000064762	Complement component 3.	Complement C4-A-like.	0.590
C3	LOC462577	ENSPTRP00000017648	ENSPTRP00000064661	Complement component 3.	C4B isoform 1.	0.957