STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC1AStructural maintenance of chromosomes protein. (1233 aa)    
Predicted Functional Partners:
RAD21
RAD21 cohesin complex component.
   
 0.999
STAG2
Stromal antigen 2.
   
 0.999
SMC3
Structural maintenance of chromosomes protein.
   
0.999
STAG1
Stromal antigen 1.
   
 0.999
NIPBL
Nipped-B protein.
   
 0.995
REC8
Meiotic recombination protein REC8-like 1.
   
 0.992
PDS5A
PDS5, regulator of cohesion maintenance, homolog A.
   
 0.980
SNPH
Double-strand-break repair protein rad21-like protein 1 isoform X1.
   
 0.979
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.977
PDS5B
PDS5, regulator of cohesion maintenance, homolog B.
   
 0.976
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.