LPAR4 protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	GNAQ	ENSPTRP00000003543	ENSPTRP00000049267	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.518
AGT	LPAR1	ENSPTRP00000003543	ENSPTRP00000063334	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.920
AGT	LPAR2	ENSPTRP00000003543	ENSPTRP00000040364	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Lysophosphatidic acid receptor 2.	0.917
AGT	LPAR3	ENSPTRP00000003543	ENSPTRP00000001564	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Lysophosphatidic acid receptor 3.	0.918
AGT	LPAR4	ENSPTRP00000003543	ENSPTRP00000037935	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Lysophosphatidic acid receptor 4.	0.917
AGT	LPAR6	ENSPTRP00000003543	ENSPTRP00000009975	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Lysophosphatidic acid receptor 6.	0.917
CHRM1	CHRM2	ENSPTRP00000006519	ENSPTRP00000086632	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	0.906
CHRM1	GNAQ	ENSPTRP00000006519	ENSPTRP00000049267	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.949
CHRM1	LPAR1	ENSPTRP00000006519	ENSPTRP00000063334	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.915
CHRM1	LPAR2	ENSPTRP00000006519	ENSPTRP00000040364	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Lysophosphatidic acid receptor 2.	0.911
CHRM1	LPAR3	ENSPTRP00000006519	ENSPTRP00000001564	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Lysophosphatidic acid receptor 3.	0.913
CHRM1	LPAR4	ENSPTRP00000006519	ENSPTRP00000037935	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Lysophosphatidic acid receptor 4.	0.909
CHRM1	LPAR6	ENSPTRP00000006519	ENSPTRP00000009975	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Lysophosphatidic acid receptor 6.	0.906
CHRM2	CHRM1	ENSPTRP00000086632	ENSPTRP00000006519	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.906
CHRM2	GNAQ	ENSPTRP00000086632	ENSPTRP00000049267	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Guanine nucleotide binding protein (G protein), q polypeptide.	0.749
CHRM2	LPAR1	ENSPTRP00000086632	ENSPTRP00000063334	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.915
CHRM2	LPAR2	ENSPTRP00000086632	ENSPTRP00000040364	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Lysophosphatidic acid receptor 2.	0.909
CHRM2	LPAR3	ENSPTRP00000086632	ENSPTRP00000001564	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Lysophosphatidic acid receptor 3.	0.919
CHRM2	LPAR4	ENSPTRP00000086632	ENSPTRP00000037935	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Lysophosphatidic acid receptor 4.	0.911
CHRM2	LPAR6	ENSPTRP00000086632	ENSPTRP00000009975	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Lysophosphatidic acid receptor 6.	0.911