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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDH11XProtocadherin-11 X-linked; Potential calcium-dependent cell-adhesion protein. (1347 aa)    
Predicted Functional Partners:
TGIF2LX
Homeobox protein TGIF2LX; May have a transcription role in testis; Belongs to the TALE/TGIF homeobox family.
      
 0.779
ARL13A
ADP ribosylation factor like GTPase 13A.
   
  
 0.755
ZFX
Zinc finger protein X-linked.
   
 
 0.702
AMELX
Amelogenin X-linked.
   
  
 0.696
HSPB7
Heat shock 27kDa protein family, member 7 (Cardiovascular); Belongs to the small heat shock protein (HSP20) family.
      
 0.682
AMELY
Amelogenin, Y isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity). Belongs to the amelogenin family.
   
  
 0.679
TNFSF18
Tumor necrosis factor ligand 2A.
   
  
 0.677
PRKX
Protein kinase, X-linked; Belongs to the protein kinase superfamily.
   
  
 0.672
PABPC5
Polyadenylate-binding protein 5; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
      
 0.667
PRKY
Serine/threonine-protein kinase PRKX.
   
  
 0.657
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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