| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASAH1 | CMAH | ENSPTRP00000063559 | ENSPTRP00000030365 | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. | 0.688 |
| ASAH1 | GLRA4 | ENSPTRP00000063559 | ENSPTRP00000038072 | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.710 |
| ASAH1 | KRT41 | ENSPTRP00000063559 | ENSPTRP00000054593 | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] | Type I keratin, acidic. | 0.517 |
| ASAH1 | ZNF850 | ENSPTRP00000063559 | ENSPTRP00000091205 | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] | ZNF850 isoform 3. | 0.490 |
| CMAH | ASAH1 | ENSPTRP00000030365 | ENSPTRP00000063559 | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] | 0.688 |
| CMAH | GLRA4 | ENSPTRP00000030365 | ENSPTRP00000038072 | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.651 |
| CMAH | KRT41 | ENSPTRP00000030365 | ENSPTRP00000054593 | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. | Type I keratin, acidic. | 0.406 |
| CMAH | ZNF850 | ENSPTRP00000030365 | ENSPTRP00000091205 | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. | ZNF850 isoform 3. | 0.437 |
| GLRA4 | ASAH1 | ENSPTRP00000038072 | ENSPTRP00000063559 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (By similarity). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (By similarity). Has a higher catalytic efficiency towards C12-ceramides versus other ceramides (By similarity). Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatt [...] | 0.710 |
| GLRA4 | CMAH | ENSPTRP00000038072 | ENSPTRP00000030365 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells. | 0.651 |
| GLRA4 | GLRB | ENSPTRP00000038072 | ENSPTRP00000072009 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Glycine receptor, beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.670 |
| GLRA4 | GPHN | ENSPTRP00000038072 | ENSPTRP00000089887 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.656 |
| GLRA4 | KRT41 | ENSPTRP00000038072 | ENSPTRP00000054593 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Type I keratin, acidic. | 0.766 |
| GLRA4 | LOC461609 | ENSPTRP00000038072 | ENSPTRP00000071035 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | 0.704 |
| GLRA4 | PLK5 | ENSPTRP00000038072 | ENSPTRP00000061423 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | PLK5 isoform 3. | 0.764 |
| GLRA4 | PLP1 | ENSPTRP00000038072 | ENSPTRP00000038073 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Proteolipid protein 1. | 0.700 |
| GLRA4 | RIBC2 | ENSPTRP00000038072 | ENSPTRP00000024982 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | RIB43A domain with coiled-coils 2. | 0.648 |
| GLRA4 | ZNF850 | ENSPTRP00000038072 | ENSPTRP00000091205 | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | ZNF850 isoform 3. | 0.767 |
| GLRB | GLRA4 | ENSPTRP00000072009 | ENSPTRP00000038072 | Glycine receptor, beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.670 |
| GLRB | GPHN | ENSPTRP00000072009 | ENSPTRP00000089887 | Glycine receptor, beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.931 |
