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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VGLL1Vestigial like family member 1. (258 aa)    
Predicted Functional Partners:
TEAD4
Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
    
 
 0.933
TEAD1
TEAD1 isoform 6.
    
 
 0.883
VGLL4
Vestigial like family member 4.
      
 0.735
TEAD3
TEA domain transcription factor 3.
    
 
 0.722
CAPN6
CAPN6 isoform 1; Belongs to the peptidase C2 family.
      
 0.658
TEAD2
TEA domain transcription factor 2.
    
 
 0.644
WWTR1
WW domain containing transcription regulator 1.
      
 0.631
GYG2
GYG2 isoform 2.
      
 0.603
APLNR
APLNR isoform 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.597
BHLHE40
Basic helix-loop-helix family, member e40.
      
 0.576
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.