STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHD4Chromodomain helicase DNA binding protein 4. (1912 aa)    
Predicted Functional Partners:
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.996
RBBP7
RBBP7 isoform 5.
   
 0.994
MTA1
Metastasis associated 1.
   
 0.994
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.993
CHD3
Chromodomain helicase DNA binding protein 3.
  
0.990
GATAD2B
GATAD2B isoform 3.
   
 0.987
MTA3
Metastasis associated 1 family member 3.
   
 0.985
MTA2
Metastasis associated 1 family, member 2.
   
 0.980
ENSPTRP00000072489
annotation not available
   
 0.980
GATAD2A
GATA zinc finger domain containing 2A.
   
 0.978
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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