| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HDAC4 | MEF2B | ENSPTRP00000073000 | ENSPTRP00000018308 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | MADS-box transcription enhancer factor 2B. | 0.530 |
| HDAC4 | MEF2C | ENSPTRP00000073000 | ENSPTRP00000090496 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | Myocyte enhancer factor 2C. | 0.940 |
| HDAC4 | MEF2D | ENSPTRP00000073000 | ENSPTRP00000074200 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | Myocyte enhancer factor 2D. | 0.904 |
| MAPK11 | MAPK12 | ENSPTRP00000074484 | ENSPTRP00000055595 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase. | 0.971 |
| MAPK11 | MAPK14 | ENSPTRP00000074484 | ENSPTRP00000030915 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | 0.929 |
| MAPK11 | MEF2B | ENSPTRP00000074484 | ENSPTRP00000018308 | Mitogen-activated protein kinase. | MADS-box transcription enhancer factor 2B. | 0.708 |
| MAPK11 | MEF2C | ENSPTRP00000074484 | ENSPTRP00000090496 | Mitogen-activated protein kinase. | Myocyte enhancer factor 2C. | 0.976 |
| MAPK11 | MEF2D | ENSPTRP00000074484 | ENSPTRP00000074200 | Mitogen-activated protein kinase. | Myocyte enhancer factor 2D. | 0.724 |
| MAPK12 | MAPK11 | ENSPTRP00000055595 | ENSPTRP00000074484 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase. | 0.971 |
| MAPK12 | MAPK14 | ENSPTRP00000055595 | ENSPTRP00000030915 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | 0.952 |
| MAPK12 | MEF2B | ENSPTRP00000055595 | ENSPTRP00000018308 | Mitogen-activated protein kinase. | MADS-box transcription enhancer factor 2B. | 0.738 |
| MAPK12 | MEF2C | ENSPTRP00000055595 | ENSPTRP00000090496 | Mitogen-activated protein kinase. | Myocyte enhancer factor 2C. | 0.974 |
| MAPK12 | MEF2D | ENSPTRP00000055595 | ENSPTRP00000074200 | Mitogen-activated protein kinase. | Myocyte enhancer factor 2D. | 0.768 |
| MAPK14 | MAPK11 | ENSPTRP00000030915 | ENSPTRP00000074484 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | Mitogen-activated protein kinase. | 0.929 |
| MAPK14 | MAPK12 | ENSPTRP00000030915 | ENSPTRP00000055595 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | Mitogen-activated protein kinase. | 0.952 |
| MAPK14 | MEF2B | ENSPTRP00000030915 | ENSPTRP00000018308 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | MADS-box transcription enhancer factor 2B. | 0.629 |
| MAPK14 | MEF2C | ENSPTRP00000030915 | ENSPTRP00000090496 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | Myocyte enhancer factor 2C. | 0.971 |
| MAPK14 | MEF2D | ENSPTRP00000030915 | ENSPTRP00000074200 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | Myocyte enhancer factor 2D. | 0.646 |
| MAPK14 | NFATC3 | ENSPTRP00000030915 | ENSPTRP00000087510 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. | 0.408 |
| MEF2B | HDAC4 | ENSPTRP00000018308 | ENSPTRP00000073000 | MADS-box transcription enhancer factor 2B. | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | 0.530 |