STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMOTL2AMOTL2 isoform 6. (837 aa)    
Predicted Functional Partners:
NF2
Neurofibromin 2 (Merlin).
    
 0.979
YAP1
Yes-associated protein 1.
   
 0.954
AMOT
AMOT isoform 2.
    
0.939
PATJ
PATJ isoform 2.
   
 0.937
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
   
 0.925
AMOTL1
Angiomotin like 1.
    
0.913
PRKCI
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
  0.905
LATS2
Non-specific serine/threonine protein kinase.
   
 0.846
WWTR1
WW domain containing transcription regulator 1.
   
 0.843
LATS1
LATS, large tumor suppressor, homolog 1.
   
 0.784
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.