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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLGN4XNeuroligin 4 X-linked. (817 aa)    
Predicted Functional Partners:
NRXN2
NRXN2 isoform 2.
   
 0.996
NRXN1
NRXN1 isoform 9.
   
 0.992
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.912
SHANK3
SHANK3 isoform 2.
   
 0.832
SHANK2
SH3 and multiple ankyrin repeat domains 2.
    
 0.824
NRXN3
NRXN3 isoform 1.
   
 0.797
ENSPTRP00000063424
annotation not available
   
 0.776
PRKX
Protein kinase, X-linked; Belongs to the protein kinase superfamily.
   
 
 0.765
TBL1X
Transducin (Beta)-like 1X-linked.
   
  
 0.749
PRKY
Serine/threonine-protein kinase PRKX.
   
 
 0.738
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.