FCGR2A protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	FCGR1A	ENSPTRP00000054833	ENSPTRP00000002095	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	FCGR1A isoform 2.	0.410
CD4	FCGR2A	ENSPTRP00000054833	ENSPTRP00000040980	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Low affinity immunoglobulin gamma Fc region receptor II-a; Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens (By similarity).	0.865
CD4	HCK	ENSPTRP00000054833	ENSPTRP00000022925	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.863
CD4	LOC745350	ENSPTRP00000054833	ENSPTRP00000084431	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	FCGR3A isoform 2.	0.573
CD4	LYN	ENSPTRP00000054833	ENSPTRP00000046608	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.755
CD4	SRC	ENSPTRP00000054833	ENSPTRP00000076797	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.802
CD4	SYK	ENSPTRP00000054833	ENSPTRP00000074883	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.845
CK820_G0041990	FCGR1A	ENSPTRP00000019709	ENSPTRP00000002095	LILRA1 isoform 3.	FCGR1A isoform 2.	0.825
CK820_G0041990	FCGR2A	ENSPTRP00000019709	ENSPTRP00000040980	LILRA1 isoform 3.	Low affinity immunoglobulin gamma Fc region receptor II-a; Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens (By similarity).	0.843
CK820_G0041990	LOC745350	ENSPTRP00000019709	ENSPTRP00000084431	LILRA1 isoform 3.	FCGR3A isoform 2.	0.822
CK820_G0041990	SYK	ENSPTRP00000019709	ENSPTRP00000074883	LILRA1 isoform 3.	Tyrosine-protein kinase.	0.908
FCGR1A	CD4	ENSPTRP00000002095	ENSPTRP00000054833	FCGR1A isoform 2.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.410
FCGR1A	CK820_G0041990	ENSPTRP00000002095	ENSPTRP00000019709	FCGR1A isoform 2.	LILRA1 isoform 3.	0.825
FCGR1A	FCGR2A	ENSPTRP00000002095	ENSPTRP00000040980	FCGR1A isoform 2.	Low affinity immunoglobulin gamma Fc region receptor II-a; Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens (By similarity).	0.930
FCGR1A	HCK	ENSPTRP00000002095	ENSPTRP00000022925	FCGR1A isoform 2.	Tyrosine-protein kinase.	0.941
FCGR1A	LILRA2-2	ENSPTRP00000002095	ENSPTRP00000067796	FCGR1A isoform 2.	LILRA2 isoform 3.	0.827
FCGR1A	LILRB1	ENSPTRP00000002095	ENSPTRP00000019708	FCGR1A isoform 2.	LILRB1 isoform 3.	0.814
FCGR1A	LOC745350	ENSPTRP00000002095	ENSPTRP00000084431	FCGR1A isoform 2.	FCGR3A isoform 2.	0.941
FCGR1A	LYN	ENSPTRP00000002095	ENSPTRP00000046608	FCGR1A isoform 2.	Tyrosine-protein kinase.	0.941
FCGR1A	SRC	ENSPTRP00000002095	ENSPTRP00000076797	FCGR1A isoform 2.	Tyrosine-protein kinase.	0.935