STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPTRP00000043431Caspase recruitment domain-containing protein 16/17/18. (352 aa)    
Predicted Functional Partners:
CARD16
Caspase recruitment domain-containing protein 16 isoform X4.
  
0.962
PYCARD
PYD and CARD domain containing.
   
 0.936
GSDMD
GSDMD isoform 4.
   
 0.915
CASP1
CASP1 isoform 4; Belongs to the peptidase C14A family.
  
  
 
0.901
NAIP
NLR family apoptosis inhibitory protein.
   
 0.789
NLRP1
NLR family, pyrin domain containing 1.
   
 0.759
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
 0.755
AIM2
Absent in melanoma 2.
   
 0.740
PYDC5
Pyrin domain-only protein 3.
   
 0.740
NLRP6
NLR family pyrin domain containing 6.
   
 0.728
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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