SETDB2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SETDB2

SET domain bifurcated histone lysine methyltransferase 2. (719 aa)

Predicted Functional Partners:

ATF7IP

0.861

ARL14EP

0.844

PHF11

0.812

ATF7IP2

0.800

ZMYM6

0.764

RCBTB2

0.740

FNDC3A

0.740

ITM2B

0.730

CDADC1

0.730

CAB39L

0.730

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL14EP	ATF7IP	ENSPTRP00000006021	ENSPTRP00000008061	ADP ribosylation factor like GTPase 14 effector protein.	ATF7IP isoform 3.	0.880
ARL14EP	ATF7IP2	ENSPTRP00000006021	ENSPTRP00000073329	ADP ribosylation factor like GTPase 14 effector protein.	Activating transcription factor 7 interacting protein 2.	0.707
ARL14EP	SETDB2	ENSPTRP00000006021	ENSPTRP00000042655	ADP ribosylation factor like GTPase 14 effector protein.	SET domain bifurcated histone lysine methyltransferase 2.	0.844
ATF7IP	ARL14EP	ENSPTRP00000008061	ENSPTRP00000006021	ATF7IP isoform 3.	ADP ribosylation factor like GTPase 14 effector protein.	0.880
ATF7IP	ATF7IP2	ENSPTRP00000008061	ENSPTRP00000073329	ATF7IP isoform 3.	Activating transcription factor 7 interacting protein 2.	0.533
ATF7IP	SETDB2	ENSPTRP00000008061	ENSPTRP00000042655	ATF7IP isoform 3.	SET domain bifurcated histone lysine methyltransferase 2.	0.861
ATF7IP2	ARL14EP	ENSPTRP00000073329	ENSPTRP00000006021	Activating transcription factor 7 interacting protein 2.	ADP ribosylation factor like GTPase 14 effector protein.	0.707
ATF7IP2	ATF7IP	ENSPTRP00000073329	ENSPTRP00000008061	Activating transcription factor 7 interacting protein 2.	ATF7IP isoform 3.	0.533
ATF7IP2	SETDB2	ENSPTRP00000073329	ENSPTRP00000042655	Activating transcription factor 7 interacting protein 2.	SET domain bifurcated histone lysine methyltransferase 2.	0.800
CAB39L	CDADC1	ENSPTRP00000009989	ENSPTRP00000009987	Calcium-binding protein 39-like.	Cytidine and dCMP deaminase domain containing 1.	0.788
CAB39L	FNDC3A	ENSPTRP00000009989	ENSPTRP00000083936	Calcium-binding protein 39-like.	Fibronectin type III domain containing 3A.	0.788
CAB39L	ITM2B	ENSPTRP00000009989	ENSPTRP00000009973	Calcium-binding protein 39-like.	Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity). Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers; Belongs to the ITM2 family.	0.788
CAB39L	PHF11	ENSPTRP00000009989	ENSPTRP00000053515	Calcium-binding protein 39-like.	PHD finger protein 11.	0.699
CAB39L	RCBTB2	ENSPTRP00000009989	ENSPTRP00000072566	Calcium-binding protein 39-like.	RCC1 and BTB domain containing protein 2.	0.789
CAB39L	SETDB2	ENSPTRP00000009989	ENSPTRP00000042655	Calcium-binding protein 39-like.	SET domain bifurcated histone lysine methyltransferase 2.	0.730
CDADC1	CAB39L	ENSPTRP00000009987	ENSPTRP00000009989	Cytidine and dCMP deaminase domain containing 1.	Calcium-binding protein 39-like.	0.788
CDADC1	FNDC3A	ENSPTRP00000009987	ENSPTRP00000083936	Cytidine and dCMP deaminase domain containing 1.	Fibronectin type III domain containing 3A.	0.788
CDADC1	ITM2B	ENSPTRP00000009987	ENSPTRP00000009973	Cytidine and dCMP deaminase domain containing 1.	Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity). Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers; Belongs to the ITM2 family.	0.788
CDADC1	PHF11	ENSPTRP00000009987	ENSPTRP00000053515	Cytidine and dCMP deaminase domain containing 1.	PHD finger protein 11.	0.703
CDADC1	RCBTB2	ENSPTRP00000009987	ENSPTRP00000072566	Cytidine and dCMP deaminase domain containing 1.	RCC1 and BTB domain containing protein 2.	0.799