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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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CYP2D6Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] (488 aa)    
Predicted Functional Partners:
UGT2B7
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.954
CYP3A4
Cytochrome P450 family 3 subfamily A member 4.
  
0.954
CYP2A7
CYP2A6 isoform 1; Belongs to the cytochrome P450 family.
  
0.940
UGT2A3
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.940
UGT2B4
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.939
UGT2B10
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.938
CBR3
Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.936
MAOA
Amine oxidase.
   
 0.935
LOC101058187
CYP2A13 isoform 1; Belongs to the cytochrome P450 family.
  
 
0.935
CYP1A1
Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
0.934
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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