| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATRX | SMC5 | ENSPTRP00000087577 | ENSPTRP00000042849 | Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...] | Structural maintenance of chromosomes 5. | 0.870 |
| DDB1 | NSMCE1 | ENSPTRP00000081878 | ENSPTRP00000013521 | Damage-specific DNA binding protein 1, 127kDa. | NSE1 homolog, SMC5-SMC6 complex component. | 0.573 |
| DDB1 | NSMCE2 | ENSPTRP00000081878 | ENSPTRP00000035182 | Damage-specific DNA binding protein 1, 127kDa. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.778 |
| DDB1 | NSMCE4A | ENSPTRP00000081878 | ENSPTRP00000005315 | Damage-specific DNA binding protein 1, 127kDa. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.536 |
| DDB1 | SMC5 | ENSPTRP00000081878 | ENSPTRP00000042849 | Damage-specific DNA binding protein 1, 127kDa. | Structural maintenance of chromosomes 5. | 0.933 |
| DDB1 | SMC6 | ENSPTRP00000081878 | ENSPTRP00000078993 | Damage-specific DNA binding protein 1, 127kDa. | Structural maintenance of chromosomes 6. | 0.768 |
| MAGEF1 | NSMCE1 | ENSPTRP00000027009 | ENSPTRP00000013521 | Melanoma antigen family F, 1. | NSE1 homolog, SMC5-SMC6 complex component. | 0.882 |
| MAGEF1 | NSMCE2 | ENSPTRP00000027009 | ENSPTRP00000035182 | Melanoma antigen family F, 1. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.842 |
| MAGEF1 | NSMCE4A | ENSPTRP00000027009 | ENSPTRP00000005315 | Melanoma antigen family F, 1. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.822 |
| MAGEF1 | SMC3 | ENSPTRP00000027009 | ENSPTRP00000042743 | Melanoma antigen family F, 1. | Structural maintenance of chromosomes protein. | 0.420 |
| MAGEF1 | SMC5 | ENSPTRP00000027009 | ENSPTRP00000042849 | Melanoma antigen family F, 1. | Structural maintenance of chromosomes 5. | 0.851 |
| MAGEF1 | SMC6 | ENSPTRP00000027009 | ENSPTRP00000078993 | Melanoma antigen family F, 1. | Structural maintenance of chromosomes 6. | 0.850 |
| MAGEF1 | ZNF597 | ENSPTRP00000027009 | ENSPTRP00000013145 | Melanoma antigen family F, 1. | Zinc finger protein 597. | 0.563 |
| NSMCE1 | DDB1 | ENSPTRP00000013521 | ENSPTRP00000081878 | NSE1 homolog, SMC5-SMC6 complex component. | Damage-specific DNA binding protein 1, 127kDa. | 0.573 |
| NSMCE1 | MAGEF1 | ENSPTRP00000013521 | ENSPTRP00000027009 | NSE1 homolog, SMC5-SMC6 complex component. | Melanoma antigen family F, 1. | 0.882 |
| NSMCE1 | NSMCE2 | ENSPTRP00000013521 | ENSPTRP00000035182 | NSE1 homolog, SMC5-SMC6 complex component. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.999 |
| NSMCE1 | NSMCE4A | ENSPTRP00000013521 | ENSPTRP00000005315 | NSE1 homolog, SMC5-SMC6 complex component. | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. | 0.998 |
| NSMCE1 | SLF1 | ENSPTRP00000013521 | ENSPTRP00000029231 | NSE1 homolog, SMC5-SMC6 complex component. | SLF1 isoform 2. | 0.852 |
| NSMCE1 | SMC3 | ENSPTRP00000013521 | ENSPTRP00000042743 | NSE1 homolog, SMC5-SMC6 complex component. | Structural maintenance of chromosomes protein. | 0.860 |
| NSMCE1 | SMC5 | ENSPTRP00000013521 | ENSPTRP00000042849 | NSE1 homolog, SMC5-SMC6 complex component. | Structural maintenance of chromosomes 5. | 0.999 |
