ENSPTRP00000043431 protein (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIM2	CARD16	ENSPTRP00000051692	ENSPTRP00000063535	Absent in melanoma 2.	Caspase recruitment domain-containing protein 16 isoform X4.	0.950
AIM2	CARD8	ENSPTRP00000051692	ENSPTRP00000068031	Absent in melanoma 2.	Caspase recruitment domain family member 8.	0.775
AIM2	CASP1	ENSPTRP00000051692	ENSPTRP00000078835	Absent in melanoma 2.	CASP1 isoform 4; Belongs to the peptidase C14A family.	0.996
AIM2	ENSPTRP00000043431	ENSPTRP00000051692	ENSPTRP00000043431	Absent in melanoma 2.	Caspase recruitment domain-containing protein 16/17/18.	0.972
AIM2	GSDMD	ENSPTRP00000051692	ENSPTRP00000035317	Absent in melanoma 2.	GSDMD isoform 4.	0.788
AIM2	IL1B	ENSPTRP00000051692	ENSPTRP00000021191	Absent in melanoma 2.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.605
AIM2	NAIP	ENSPTRP00000051692	ENSPTRP00000048273	Absent in melanoma 2.	NLR family apoptosis inhibitory protein.	0.778
AIM2	NLRC4	ENSPTRP00000051692	ENSPTRP00000041889	Absent in melanoma 2.	NLR family CARD domain containing 4.	0.873
AIM2	NLRP3	ENSPTRP00000051692	ENSPTRP00000003728	Absent in melanoma 2.	NLRP3 isoform 2.	0.573
AIM2	PYCARD	ENSPTRP00000051692	ENSPTRP00000013732	Absent in melanoma 2.	PYD and CARD domain containing.	0.997
CARD16	AIM2	ENSPTRP00000063535	ENSPTRP00000051692	Caspase recruitment domain-containing protein 16 isoform X4.	Absent in melanoma 2.	0.950
CARD16	CARD8	ENSPTRP00000063535	ENSPTRP00000068031	Caspase recruitment domain-containing protein 16 isoform X4.	Caspase recruitment domain family member 8.	0.937
CARD16	CASP1	ENSPTRP00000063535	ENSPTRP00000078835	Caspase recruitment domain-containing protein 16 isoform X4.	CASP1 isoform 4; Belongs to the peptidase C14A family.	0.992
CARD16	ENSPTRP00000043431	ENSPTRP00000063535	ENSPTRP00000043431	Caspase recruitment domain-containing protein 16 isoform X4.	Caspase recruitment domain-containing protein 16/17/18.	0.987
CARD16	GSDMD	ENSPTRP00000063535	ENSPTRP00000035317	Caspase recruitment domain-containing protein 16 isoform X4.	GSDMD isoform 4.	0.863
CARD16	IL1B	ENSPTRP00000063535	ENSPTRP00000021191	Caspase recruitment domain-containing protein 16 isoform X4.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.844
CARD16	NAIP	ENSPTRP00000063535	ENSPTRP00000048273	Caspase recruitment domain-containing protein 16 isoform X4.	NLR family apoptosis inhibitory protein.	0.955
CARD16	NLRC4	ENSPTRP00000063535	ENSPTRP00000041889	Caspase recruitment domain-containing protein 16 isoform X4.	NLR family CARD domain containing 4.	0.812
CARD16	NLRP3	ENSPTRP00000063535	ENSPTRP00000003728	Caspase recruitment domain-containing protein 16 isoform X4.	NLRP3 isoform 2.	0.946
CARD16	PYCARD	ENSPTRP00000063535	ENSPTRP00000013732	Caspase recruitment domain-containing protein 16 isoform X4.	PYD and CARD domain containing.	0.988