STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEF2DMyocyte enhancer factor 2D. (521 aa)    
Predicted Functional Partners:
MEF2B
MADS-box transcription enhancer factor 2B.
    
0.983
MEF2C
Myocyte enhancer factor 2C.
   
0.960
NFATC2
NFATC2 isoform 4.
   
 0.919
MEF2A
Myocyte enhancer factor 2A.
  
0.913
NFATC3
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3.
   
 0.913
NFATC4
Nuclear factor of activated T cells 4.
     
 0.908
HDAC4
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 
 0.904
SRF
Serum response factor (C-fos serum response element-binding transcription factor).
     
0.886
MYOG
MYOG isoform 1.
    
 0.826
HDAC9
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 
 0.814
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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