TXNDC11 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD45	CALR	ENSPTRP00000002821	ENSPTRP00000018010	Ankyrin repeat domain 45.	Calreticulin.	0.837
ANKRD45	TXNDC11	ENSPTRP00000002821	ENSPTRP00000043609	Ankyrin repeat domain 45.	Thioredoxin domain containing 11.	0.754
CALR	ANKRD45	ENSPTRP00000018010	ENSPTRP00000002821	Calreticulin.	Ankyrin repeat domain 45.	0.837
CALR	EDEM2	ENSPTRP00000018010	ENSPTRP00000023036	Calreticulin.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.469
CALR	HSPA5	ENSPTRP00000018010	ENSPTRP00000000984	Calreticulin.	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	0.967
CALR	LOC100609513	ENSPTRP00000018010	ENSPTRP00000063056	Calreticulin.	78 kDa glucose-regulated protein pseudogene.	0.960
CALR	TXNDC11	ENSPTRP00000018010	ENSPTRP00000043609	Calreticulin.	Thioredoxin domain containing 11.	0.645
CAV1	DUOXA1	ENSPTRP00000033587	ENSPTRP00000012016	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Dual oxidase maturation factor 1.	0.781
CAV1	DUOXA2	ENSPTRP00000033587	ENSPTRP00000012013	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Dual oxidase maturation factor 2.	0.826
CAV1	TXNDC11	ENSPTRP00000033587	ENSPTRP00000043609	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Thioredoxin domain containing 11.	0.825
DUOXA1	CAV1	ENSPTRP00000012016	ENSPTRP00000033587	Dual oxidase maturation factor 1.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.781
DUOXA1	DUOXA2	ENSPTRP00000012016	ENSPTRP00000012013	Dual oxidase maturation factor 1.	Dual oxidase maturation factor 2.	0.813
DUOXA1	TXNDC11	ENSPTRP00000012016	ENSPTRP00000043609	Dual oxidase maturation factor 1.	Thioredoxin domain containing 11.	0.839
DUOXA2	CAV1	ENSPTRP00000012013	ENSPTRP00000033587	Dual oxidase maturation factor 2.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.826
DUOXA2	DUOXA1	ENSPTRP00000012013	ENSPTRP00000012016	Dual oxidase maturation factor 2.	Dual oxidase maturation factor 1.	0.813
DUOXA2	TXNDC11	ENSPTRP00000012013	ENSPTRP00000043609	Dual oxidase maturation factor 2.	Thioredoxin domain containing 11.	0.907
EDEM2	CALR	ENSPTRP00000023036	ENSPTRP00000018010	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Calreticulin.	0.469
EDEM2	FBLN7	ENSPTRP00000023036	ENSPTRP00000021175	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	FBLN7 isoform 1.	0.658
EDEM2	TXNDC11	ENSPTRP00000023036	ENSPTRP00000043609	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Thioredoxin domain containing 11.	0.912
FBLN7	EDEM2	ENSPTRP00000021175	ENSPTRP00000023036	FBLN7 isoform 1.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.658