| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPTRP00000070037 | HGS | ENSPTRP00000070037 | ENSPTRP00000016628 | annotation not available | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.884 |
| ENSPTRP00000070037 | SNF8 | ENSPTRP00000070037 | ENSPTRP00000073095 | annotation not available | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. | 0.925 |
| ENSPTRP00000070037 | STAM | ENSPTRP00000070037 | ENSPTRP00000003953 | annotation not available | Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. | 0.937 |
| ENSPTRP00000070037 | TSG101 | ENSPTRP00000070037 | ENSPTRP00000062068 | annotation not available | Tumor susceptibility 101. | 0.962 |
| ENSPTRP00000070037 | UBAP1 | ENSPTRP00000070037 | ENSPTRP00000043955 | annotation not available | UBAP1 isoform 4. | 0.959 |
| ENSPTRP00000070037 | VPS28 | ENSPTRP00000070037 | ENSPTRP00000091027 | annotation not available | VPS28 subunit of ESCRT-I. | 0.938 |
| ENSPTRP00000070037 | VPS28-2 | ENSPTRP00000070037 | ENSPTRP00000077768 | annotation not available | VPS28 isoform 16; Belongs to the VPS28 family. | 0.990 |
| ENSPTRP00000070037 | VPS36 | ENSPTRP00000070037 | ENSPTRP00000010034 | annotation not available | Vacuolar protein sorting 36 homolog. | 0.953 |
| ENSPTRP00000070037 | VPS37A | ENSPTRP00000070037 | ENSPTRP00000034271 | annotation not available | Vacuolar protein sorting 37 homolog A. | 0.900 |
| ENSPTRP00000070037 | VPS37B | ENSPTRP00000070037 | ENSPTRP00000067422 | annotation not available | Vacuolar protein sorting 37 homolog B. | 0.965 |
| HGS | ENSPTRP00000070037 | ENSPTRP00000016628 | ENSPTRP00000070037 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | annotation not available | 0.884 |
| HGS | SNF8 | ENSPTRP00000016628 | ENSPTRP00000073095 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. | 0.795 |
| HGS | STAM | ENSPTRP00000016628 | ENSPTRP00000003953 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. | 0.999 |
| HGS | TSG101 | ENSPTRP00000016628 | ENSPTRP00000062068 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.998 |
| HGS | UBAP1 | ENSPTRP00000016628 | ENSPTRP00000043955 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | UBAP1 isoform 4. | 0.937 |
| HGS | VPS28 | ENSPTRP00000016628 | ENSPTRP00000091027 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS28 subunit of ESCRT-I. | 0.932 |
| HGS | VPS28-2 | ENSPTRP00000016628 | ENSPTRP00000077768 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS28 isoform 16; Belongs to the VPS28 family. | 0.932 |
| HGS | VPS36 | ENSPTRP00000016628 | ENSPTRP00000010034 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 36 homolog. | 0.873 |
| HGS | VPS37A | ENSPTRP00000016628 | ENSPTRP00000034271 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 37 homolog A. | 0.884 |
| HGS | VPS37B | ENSPTRP00000016628 | ENSPTRP00000067422 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 37 homolog B. | 0.864 |
