RXRA protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MED1	NCOA1	ENSPTRP00000015490	ENSPTRP00000020127	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.754
MED1	NCOA2	ENSPTRP00000015490	ENSPTRP00000069925	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.720
MED1	NR1H3	ENSPTRP00000015490	ENSPTRP00000079039	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 1 group H member 3.	0.728
MED1	PPARA	ENSPTRP00000015490	ENSPTRP00000025003	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor alpha.	0.926
MED1	PPARD	ENSPTRP00000015490	ENSPTRP00000044222	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor delta.	0.641
MED1	PPARG	ENSPTRP00000015490	ENSPTRP00000076701	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.968
MED1	RARA	ENSPTRP00000015490	ENSPTRP00000053041	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	RARA isoform 4.	0.894
MED1	RXRA	ENSPTRP00000015490	ENSPTRP00000045122	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor, alpha.	0.986
MED1	RXRB	ENSPTRP00000015490	ENSPTRP00000030802	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor, beta.	0.926
MED1	RXRG	ENSPTRP00000015490	ENSPTRP00000081703	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor gamma.	0.944
NCOA1	MED1	ENSPTRP00000020127	ENSPTRP00000015490	Nuclear receptor coactivator.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.754
NCOA1	NCOA2	ENSPTRP00000020127	ENSPTRP00000069925	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.996
NCOA1	NR1H3	ENSPTRP00000020127	ENSPTRP00000079039	Nuclear receptor coactivator.	Nuclear receptor subfamily 1 group H member 3.	0.875
NCOA1	PPARA	ENSPTRP00000020127	ENSPTRP00000025003	Nuclear receptor coactivator.	Peroxisome proliferator-activated receptor alpha.	0.952
NCOA1	PPARD	ENSPTRP00000020127	ENSPTRP00000044222	Nuclear receptor coactivator.	Peroxisome proliferator-activated receptor delta.	0.881
NCOA1	PPARG	ENSPTRP00000020127	ENSPTRP00000076701	Nuclear receptor coactivator.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.959
NCOA1	RARA	ENSPTRP00000020127	ENSPTRP00000053041	Nuclear receptor coactivator.	RARA isoform 4.	0.931
NCOA1	RXRA	ENSPTRP00000020127	ENSPTRP00000045122	Nuclear receptor coactivator.	Retinoid X receptor, alpha.	0.993
NCOA1	RXRB	ENSPTRP00000020127	ENSPTRP00000030802	Nuclear receptor coactivator.	Retinoid X receptor, beta.	0.903
NCOA1	RXRG	ENSPTRP00000020127	ENSPTRP00000081703	Nuclear receptor coactivator.	Retinoid X receptor gamma.	0.960