TLE1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CK820_G0051198	HDAC1	ENSPTRP00000078226	ENSPTRP00000075891	TLE2 isoform 3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.540
CK820_G0051198	HDAC2	ENSPTRP00000078226	ENSPTRP00000049696	TLE2 isoform 3.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.540
CK820_G0051198	HES1	ENSPTRP00000078226	ENSPTRP00000064171	TLE2 isoform 3.	Hes family bHLH transcription factor 1.	0.471
CK820_G0051198	LEF1	ENSPTRP00000078226	ENSPTRP00000079959	TLE2 isoform 3.	Lymphoid enhancer binding factor 1.	0.726
CK820_G0051198	TLE1	ENSPTRP00000078226	ENSPTRP00000045296	TLE2 isoform 3.	Transducin-like enhancer of split 1.	0.978
CK820_G0051198	TLE3	ENSPTRP00000078226	ENSPTRP00000012367	TLE2 isoform 3.	TLE family member 3, transcriptional corepressor.	0.926
CK820_G0051198	TLE4	ENSPTRP00000078226	ENSPTRP00000071835	TLE2 isoform 3.	TLE family member 4, transcriptional corepressor.	0.970
CK820_G0051198	TLE5	ENSPTRP00000078226	ENSPTRP00000071146	TLE2 isoform 3.	AES isoform 1.	0.836
HDAC1	CK820_G0051198	ENSPTRP00000075891	ENSPTRP00000078226	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE2 isoform 3.	0.540
HDAC1	HDAC2	ENSPTRP00000075891	ENSPTRP00000049696	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.999
HDAC1	LEF1	ENSPTRP00000075891	ENSPTRP00000079959	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Lymphoid enhancer binding factor 1.	0.564
HDAC1	RBPJ	ENSPTRP00000075891	ENSPTRP00000079413	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Recombination signal binding protein for immunoglobulin kappa J region.	0.951
HDAC1	TLE1	ENSPTRP00000075891	ENSPTRP00000045296	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transducin-like enhancer of split 1.	0.956
HDAC1	TLE2	ENSPTRP00000075891	ENSPTRP00000046179	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transducin-like enhancer of split 2.	0.903
HDAC1	TLE3	ENSPTRP00000075891	ENSPTRP00000012367	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE family member 3, transcriptional corepressor.	0.920
HDAC1	TLE4	ENSPTRP00000075891	ENSPTRP00000071835	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	TLE family member 4, transcriptional corepressor.	0.903
HDAC1	TLE5	ENSPTRP00000075891	ENSPTRP00000071146	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	AES isoform 1.	0.540
HDAC2	CK820_G0051198	ENSPTRP00000049696	ENSPTRP00000078226	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	TLE2 isoform 3.	0.540
HDAC2	HDAC1	ENSPTRP00000049696	ENSPTRP00000075891	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
HDAC2	LEF1	ENSPTRP00000049696	ENSPTRP00000079959	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Lymphoid enhancer binding factor 1.	0.549