STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE1Transducin-like enhancer of split 1. (814 aa)    
Predicted Functional Partners:
TLE4
TLE family member 4, transcriptional corepressor.
  
 
0.897
TLE3
TLE family member 3, transcriptional corepressor.
  
 
0.891
FRMD3
FERM domain containing 3.
      
 0.887
RASEF
RAS and EF-hand domain containing.
    
 
 0.887
LEF1
Lymphoid enhancer binding factor 1.
    
 0.883
HES1
Hes family bHLH transcription factor 1.
    
 0.855
FOXG1
FOXG1 isoform 8.
    
 
 0.831
TLE5
AES isoform 1.
    
0.831
HES6
Hes family bHLH transcription factor 6.
    
 0.779
PSAT1
Phosphoserine aminotransferase.
      
 0.777
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.