STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIMCH1LIM and calponin homology domains 1. (1626 aa)    
Predicted Functional Partners:
LRRC23
Leucine rich repeat containing 23.
   
 
 0.556
GLI4
GLI family zinc finger 4.
    
 
 0.523
RBM4B
RBM4B isoform 1.
      
 0.522
KCNA3
KCNA3 isoform 1; Belongs to the potassium channel family.
   
 
 0.506
PHRF1
PHRF1 isoform 1.
      
 0.505
RNF44
RNF44 isoform 2.
      
 0.501
TCF25
Transcription factor 25 (Basic helix-loop-helix).
      
 0.485
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
  
 0.471
DLGAP4
DLGAP4 isoform 4.
      
 0.470
HS6ST2
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.470
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.