| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOX1 | GDA | ENSPTRP00000048899 | ENSPTRP00000072982 | Aldehyde oxidase 1. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.723 |
| AOX1 | PNP | ENSPTRP00000048899 | ENSPTRP00000010346 | Aldehyde oxidase 1. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.627 |
| DLG3 | DLG4 | ENSPTRP00000069805 | ENSPTRP00000014780 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | 0.992 |
| DLG3 | GDA | ENSPTRP00000069805 | ENSPTRP00000072982 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.759 |
| DLG4 | DLG3 | ENSPTRP00000014780 | ENSPTRP00000069805 | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | 0.992 |
| DLG4 | GDA | ENSPTRP00000014780 | ENSPTRP00000072982 | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.885 |
| ENSPTRP00000091955 | GDA | ENSPTRP00000091955 | ENSPTRP00000072982 | annotation not available | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.731 |
| ENSPTRP00000091955 | PNP | ENSPTRP00000091955 | ENSPTRP00000010346 | annotation not available | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.627 |
| GDA | AOX1 | ENSPTRP00000072982 | ENSPTRP00000048899 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Aldehyde oxidase 1. | 0.723 |
| GDA | DLG3 | ENSPTRP00000072982 | ENSPTRP00000069805 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. | 0.759 |
| GDA | DLG4 | ENSPTRP00000072982 | ENSPTRP00000014780 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | 0.885 |
| GDA | ENSPTRP00000091955 | ENSPTRP00000072982 | ENSPTRP00000091955 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | annotation not available | 0.731 |
| GDA | HAL | ENSPTRP00000072982 | ENSPTRP00000049982 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | 0.773 |
| GDA | HPRT1 | ENSPTRP00000072982 | ENSPTRP00000086770 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.932 |
| GDA | LACC1 | ENSPTRP00000072982 | ENSPTRP00000009929 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | T0067485 isoform 1. | 0.900 |
| GDA | PNP | ENSPTRP00000072982 | ENSPTRP00000010346 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.975 |
| GDA | UPRT | ENSPTRP00000072982 | ENSPTRP00000037904 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Uracil phosphoribosyltransferase homolog. | 0.769 |
| GDA | XDH | ENSPTRP00000072982 | ENSPTRP00000020275 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | XDH isoform 1. | 0.971 |
| HAL | GDA | ENSPTRP00000049982 | ENSPTRP00000072982 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.773 |
| HPRT1 | GDA | ENSPTRP00000086770 | ENSPTRP00000072982 | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.932 |
