STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYT1Synaptotagmin 1. (422 aa)    
Predicted Functional Partners:
SNAP25
Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells; Belongs to the SNAP-25 family.
   
 0.997
VAMP2
VAMP2 isoform 3.
   
 0.994
S100A13
S100 calcium binding protein A13; Belongs to the S-100 family.
    
 
 0.975
CPLX1
CPLX1 isoform 1.
   
 0.973
STX1A
STX1A isoform 3; Belongs to the syntaxin family.
   
 0.971
STX1A-2
Syntaxin 1A.
   
 0.971
RAB3A
RAB3A, member RAS oncogene family.
   
 0.967
STON2
STON2 isoform 1; Belongs to the Stoned B family.
   
 0.947
SLC17A7
SLC17A7 isoform 1.
   
 
 0.942
VAMP3
Vesicle-associated membrane protein 3 (Cellubrevin).
   
 0.931
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.