STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3BP4SH3 domain-binding protein 4. (963 aa)    
Predicted Functional Partners:
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 
 0.726
RRAGB
Ras related GTP binding B.
     
 0.723
GIPC2
GIPC2 isoform 1.
   
   0.670
GIPC1
GIPC1 isoform 3.
   
   0.616
NUMB
NUMB endocytic adaptor protein.
      
 0.565
NUMBL
NUMBL isoform 1.
      
 0.564
EFNA5
EFNA5 isoform 1; Belongs to the ephrin family.
      
 0.563
RRAGC
Ras related GTP binding C.
     
 0.542
RRAGD
Ras-related GTP binding D.
     
 0.517
CK820_G0021249
NXPH1 isoform 5.
  
    0.457
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.