PDZK1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC2	PDZK1	ENSPTRP00000077920	ENSPTRP00000046448	ATP binding cassette subfamily C member 2.	PDZK1 isoform 1.	0.735
ABCC2	SLC9A3R1	ENSPTRP00000077920	ENSPTRP00000016341	ATP binding cassette subfamily C member 2.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.684
ACE2	CFTR	ENSPTRP00000037158	ENSPTRP00000033597	Angiotensin-converting enzyme.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.614
ACE2	PDZK1	ENSPTRP00000037158	ENSPTRP00000046448	Angiotensin-converting enzyme.	PDZK1 isoform 1.	0.697
ACE2	SLC9A3R1	ENSPTRP00000037158	ENSPTRP00000016341	Angiotensin-converting enzyme.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.655
CD8B	PDZK1	ENSPTRP00000059042	ENSPTRP00000046448	CD8B isoform 3.	PDZK1 isoform 1.	0.689
CFTR	ACE2	ENSPTRP00000033597	ENSPTRP00000037158	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Angiotensin-converting enzyme.	0.614
CFTR	PDZK1	ENSPTRP00000033597	ENSPTRP00000046448	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	PDZK1 isoform 1.	0.879
CFTR	SLC9A3R1	ENSPTRP00000033597	ENSPTRP00000016341	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.996
PDZK1	ABCC2	ENSPTRP00000046448	ENSPTRP00000077920	PDZK1 isoform 1.	ATP binding cassette subfamily C member 2.	0.735
PDZK1	ACE2	ENSPTRP00000046448	ENSPTRP00000037158	PDZK1 isoform 1.	Angiotensin-converting enzyme.	0.697
PDZK1	CD8B	ENSPTRP00000046448	ENSPTRP00000059042	PDZK1 isoform 1.	CD8B isoform 3.	0.689
PDZK1	CFTR	ENSPTRP00000046448	ENSPTRP00000033597	PDZK1 isoform 1.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.879
PDZK1	PDZK1IP1	ENSPTRP00000046448	ENSPTRP00000001229	PDZK1 isoform 1.	PDZK1 interacting protein 1.	0.885
PDZK1	SCARB1	ENSPTRP00000046448	ENSPTRP00000079498	PDZK1 isoform 1.	SCARB1 isoform 8; Belongs to the CD36 family.	0.743
PDZK1	SLC17A1	ENSPTRP00000046448	ENSPTRP00000066654	PDZK1 isoform 1.	Solute carrier family 17 member 1.	0.757
PDZK1	SLC17A4	ENSPTRP00000046448	ENSPTRP00000030375	PDZK1 isoform 1.	Solute carrier family 17 member 4.	0.841
PDZK1	SLC34A1	ENSPTRP00000046448	ENSPTRP00000030034	PDZK1 isoform 1.	SLC34A1 isoform 1.	0.778
PDZK1	SLC9A3R1	ENSPTRP00000046448	ENSPTRP00000016341	PDZK1 isoform 1.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.787
PDZK1IP1	PDZK1	ENSPTRP00000001229	ENSPTRP00000046448	PDZK1 interacting protein 1.	PDZK1 isoform 1.	0.885