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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKLV-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa)    
Predicted Functional Partners:
CBL
Cas-Br-M (Murine) ecotropic retroviral transforming sequence.
    
 0.997
RAPGEF1
RAPGEF1 isoform 5.
    
 0.992
GAB1
GRB2-associated-binding protein 1.
    
 0.988
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.987
ABL1
Tyrosine-protein kinase.
    
0.985
DOCK1
DOCK1 isoform 1; Belongs to the DOCK family.
    
 0.983
EGFR
Receptor protein-tyrosine kinase.
    
 0.983
FRS2
Fibroblast growth factor receptor substrate 2.
   
 0.979
CRK
V-crk sarcoma virus CT10 oncogene homolog (Avian).
  
  
0.969
ELMO2
Engulfment and cell motility 2.
    
 0.957
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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