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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHD1LChromodomain helicase DNA binding protein 1-like. (925 aa)    
Predicted Functional Partners:
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 0.956
XPA
Xeroderma pigmentosum, complementation group A.
    
 0.886
BIVM
BIVM-ERCC5 isoform 1.
   
 0.885
H2BC11
HIST1H2BJ isoform 1.
   
 0.856
H2AC6
HIST1H2AC isoform 1.
   
 0.852
LOC462501
HIST1H2BK isoform 1.
   
 0.851
PRKAB2
Protein kinase, AMP-activated, beta 2 non-catalytic subunit.
   
 
 0.850
XRCC1
DNA repair protein XRCC1 isoform X1.
    
 0.836
APLF
Aprataxin and PNK-like factor isoform X1.
    
 
 0.835
RNF146
Ring finger protein 146.
    
 
 0.806
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.