GDI2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000074746	ENSPTRP00000087371	ENSPTRP00000074746	ENSPTRP00000087371	annotation not available	annotation not available	0.415
ENSPTRP00000074746	GDI1	ENSPTRP00000074746	ENSPTRP00000047203	annotation not available	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	0.872
ENSPTRP00000074746	GDI2	ENSPTRP00000074746	ENSPTRP00000046835	annotation not available	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.873
ENSPTRP00000074746	RAB1A	ENSPTRP00000074746	ENSPTRP00000020588	annotation not available	RAB1A, member RAS oncogene family.	0.981
ENSPTRP00000074746	RAB5A	ENSPTRP00000074746	ENSPTRP00000025327	annotation not available	RAB5A, member RAS oncogene family.	0.415
ENSPTRP00000074746	RAB5C	ENSPTRP00000074746	ENSPTRP00000078560	annotation not available	T0136450 isoform 1.	0.439
ENSPTRP00000074746	RAB8A	ENSPTRP00000074746	ENSPTRP00000018163	annotation not available	RAB8A, member RAS oncogene family.	0.734
ENSPTRP00000074746	RAB9A	ENSPTRP00000074746	ENSPTRP00000037129	annotation not available	RAB9A isoform 1.	0.405
ENSPTRP00000087371	ENSPTRP00000074746	ENSPTRP00000087371	ENSPTRP00000074746	annotation not available	annotation not available	0.415
ENSPTRP00000087371	GDI1	ENSPTRP00000087371	ENSPTRP00000047203	annotation not available	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	0.782
ENSPTRP00000087371	GDI2	ENSPTRP00000087371	ENSPTRP00000046835	annotation not available	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.840
ENSPTRP00000087371	RAB1A	ENSPTRP00000087371	ENSPTRP00000020588	annotation not available	RAB1A, member RAS oncogene family.	0.409
ENSPTRP00000087371	RAB1B	ENSPTRP00000087371	ENSPTRP00000006748	annotation not available	RAB1B, member RAS oncogene family.	0.415
ENSPTRP00000087371	RAB5C	ENSPTRP00000087371	ENSPTRP00000078560	annotation not available	T0136450 isoform 1.	0.836
ENSPTRP00000087371	RAB8A	ENSPTRP00000087371	ENSPTRP00000018163	annotation not available	RAB8A, member RAS oncogene family.	0.597
ENSPTRP00000087371	RAB9A	ENSPTRP00000087371	ENSPTRP00000037129	annotation not available	RAB9A isoform 1.	0.514
GDI1	ENSPTRP00000074746	ENSPTRP00000047203	ENSPTRP00000074746	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	annotation not available	0.872
GDI1	ENSPTRP00000087371	ENSPTRP00000047203	ENSPTRP00000087371	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	annotation not available	0.782
GDI1	GDI2	ENSPTRP00000047203	ENSPTRP00000046835	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.993
GDI1	RAB1A	ENSPTRP00000047203	ENSPTRP00000020588	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	RAB1A, member RAS oncogene family.	0.968