PIGR protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR1B1	PIGR	ENSPTRP00000033770	ENSPTRP00000046994	Aldo-keto reductase family 1, member B1 (Aldose reductase).	PIGR isoform 1.	0.704
AKR1B1	TGM4	ENSPTRP00000033770	ENSPTRP00000074592	Aldo-keto reductase family 1, member B1 (Aldose reductase).	Prostate-specific transglutaminase 4.	0.731
B4GALT1	JCHAIN	ENSPTRP00000035661	ENSPTRP00000085082	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1.	Joining chain of multimeric IgA and IgM.	0.550
B4GALT1	PIGA	ENSPTRP00000035661	ENSPTRP00000037149	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1.	Phosphatidylinositol glycan anchor biosynthesis, class A.	0.595
B4GALT1	PIGR	ENSPTRP00000035661	ENSPTRP00000046994	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1.	PIGR isoform 1.	0.778
CD4	FCAR	ENSPTRP00000054833	ENSPTRP00000075664	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Fc fragment of IgA receptor.	0.401
CD4	JCHAIN	ENSPTRP00000054833	ENSPTRP00000085082	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Joining chain of multimeric IgA and IgM.	0.672
CD4	PIGR	ENSPTRP00000054833	ENSPTRP00000046994	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	PIGR isoform 1.	0.713
FCAR	CD4	ENSPTRP00000075664	ENSPTRP00000054833	Fc fragment of IgA receptor.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.401
FCAR	JCHAIN	ENSPTRP00000075664	ENSPTRP00000085082	Fc fragment of IgA receptor.	Joining chain of multimeric IgA and IgM.	0.580
FCAR	PIGR	ENSPTRP00000075664	ENSPTRP00000046994	Fc fragment of IgA receptor.	PIGR isoform 1.	0.728
JCHAIN	B4GALT1	ENSPTRP00000085082	ENSPTRP00000035661	Joining chain of multimeric IgA and IgM.	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1.	0.550
JCHAIN	CD4	ENSPTRP00000085082	ENSPTRP00000054833	Joining chain of multimeric IgA and IgM.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.672
JCHAIN	FCAR	ENSPTRP00000085082	ENSPTRP00000075664	Joining chain of multimeric IgA and IgM.	Fc fragment of IgA receptor.	0.580
JCHAIN	PIGA	ENSPTRP00000085082	ENSPTRP00000037149	Joining chain of multimeric IgA and IgM.	Phosphatidylinositol glycan anchor biosynthesis, class A.	0.933
JCHAIN	PIGR	ENSPTRP00000085082	ENSPTRP00000046994	Joining chain of multimeric IgA and IgM.	PIGR isoform 1.	0.990
JCHAIN	Pt-FCAR	ENSPTRP00000085082	ENSPTRP00000009446	Joining chain of multimeric IgA and IgM.	FCAR isoform 1.	0.580
MIS12	PIGR	ENSPTRP00000057455	ENSPTRP00000046994	MIS12, MIND kinetochore complex component, homolog.	PIGR isoform 1.	0.809
PIGA	B4GALT1	ENSPTRP00000037149	ENSPTRP00000035661	Phosphatidylinositol glycan anchor biosynthesis, class A.	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1.	0.595
PIGA	JCHAIN	ENSPTRP00000037149	ENSPTRP00000085082	Phosphatidylinositol glycan anchor biosynthesis, class A.	Joining chain of multimeric IgA and IgM.	0.933