RXFP1 protein (Pan troglodytes) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

RXFP1

RXFP1 isoform 5. (779 aa)

Predicted Functional Partners:

RLN2

0.999

RLN1

0.994

RLN3

0.991

JAK3-2

0.985

RXFP4

0.976

RXFP3

0.967

RXFP2

0.944

GNAS

0.943

LOC104003639

0.926

INSL5

0.921

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAS	LOC104003639	ENSPTRP00000059419	ENSPTRP00000063078	GNAS isoform 19.	Guanine nucleotide-binding protein G(s) subunit alpha.	0.955
GNAS	RXFP1	ENSPTRP00000059419	ENSPTRP00000047055	GNAS isoform 19.	RXFP1 isoform 5.	0.943
GNAS	RXFP2	ENSPTRP00000059419	ENSPTRP00000009804	GNAS isoform 19.	Relaxin family peptide receptor 2.	0.936
INSL5	JAK3-2	ENSPTRP00000001444	ENSPTRP00000090239	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	0.948
INSL5	RLN1	ENSPTRP00000001444	ENSPTRP00000054896	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix; Belongs to the insulin family.	0.978
INSL5	RLN2	ENSPTRP00000001444	ENSPTRP00000035498	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.	0.988
INSL5	RLN3	ENSPTRP00000001444	ENSPTRP00000018051	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142) (By similarity).	0.996
INSL5	RXFP1	ENSPTRP00000001444	ENSPTRP00000047055	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	RXFP1 isoform 5.	0.921
INSL5	RXFP2	ENSPTRP00000001444	ENSPTRP00000009804	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	Relaxin family peptide receptor 2.	0.843
INSL5	RXFP3	ENSPTRP00000001444	ENSPTRP00000028769	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	Relaxin family peptide receptor 3.	0.906
INSL5	RXFP4	ENSPTRP00000001444	ENSPTRP00000002435	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	Relaxin family peptide/INSL5 receptor 4.	0.995
JAK3-2	INSL5	ENSPTRP00000090239	ENSPTRP00000001444	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	0.948
JAK3-2	RLN1	ENSPTRP00000090239	ENSPTRP00000054896	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix; Belongs to the insulin family.	0.989
JAK3-2	RLN2	ENSPTRP00000090239	ENSPTRP00000035498	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.	0.996
JAK3-2	RLN3	ENSPTRP00000090239	ENSPTRP00000018051	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142) (By similarity).	0.981
JAK3-2	RXFP1	ENSPTRP00000090239	ENSPTRP00000047055	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	RXFP1 isoform 5.	0.985
JAK3-2	RXFP2	ENSPTRP00000090239	ENSPTRP00000009804	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	Relaxin family peptide receptor 2.	0.999
JAK3-2	RXFP3	ENSPTRP00000090239	ENSPTRP00000028769	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	Relaxin family peptide receptor 3.	0.839
JAK3-2	RXFP4	ENSPTRP00000090239	ENSPTRP00000002435	Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).	Relaxin family peptide/INSL5 receptor 4.	0.863
LOC104003639	GNAS	ENSPTRP00000063078	ENSPTRP00000059419	Guanine nucleotide-binding protein G(s) subunit alpha.	GNAS isoform 19.	0.955