| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTRC | CLSPN | ENSPTRP00000077054 | ENSPTRP00000047143 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | CLSPN isoform 1. | 0.944 |
| CDC45 | CDC7 | ENSPTRP00000024215 | ENSPTRP00000069321 | CDC45 isoform 5. | Cell division cycle 7 homolog. | 0.936 |
| CDC45 | CHEK1 | ENSPTRP00000024215 | ENSPTRP00000067296 | CDC45 isoform 5. | CHEK1 isoform 10. | 0.971 |
| CDC45 | CLSPN | ENSPTRP00000024215 | ENSPTRP00000047143 | CDC45 isoform 5. | CLSPN isoform 1. | 0.967 |
| CDC45 | MCM10 | ENSPTRP00000024215 | ENSPTRP00000044662 | CDC45 isoform 5. | Minichromosome maintenance complex component 10. | 0.995 |
| CDC45 | MCM2 | ENSPTRP00000024215 | ENSPTRP00000026448 | CDC45 isoform 5. | DNA helicase; Belongs to the MCM family. | 0.997 |
| CDC45 | PRIMPOL | ENSPTRP00000024215 | ENSPTRP00000028539 | CDC45 isoform 5. | Coiled-coil domain containing 111. | 0.402 |
| CDC45 | RPA1 | ENSPTRP00000024215 | ENSPTRP00000014573 | CDC45 isoform 5. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.876 |
| CDC45 | TIMELESS | ENSPTRP00000024215 | ENSPTRP00000042163 | CDC45 isoform 5. | Timeless circadian regulator. | 0.890 |
| CDC45 | TOPBP1 | ENSPTRP00000024215 | ENSPTRP00000026557 | CDC45 isoform 5. | Topoisomerase (DNA) II binding protein 1. | 0.924 |
| CDC7 | CDC45 | ENSPTRP00000069321 | ENSPTRP00000024215 | Cell division cycle 7 homolog. | CDC45 isoform 5. | 0.936 |
| CDC7 | CHEK1 | ENSPTRP00000069321 | ENSPTRP00000067296 | Cell division cycle 7 homolog. | CHEK1 isoform 10. | 0.900 |
| CDC7 | CLSPN | ENSPTRP00000069321 | ENSPTRP00000047143 | Cell division cycle 7 homolog. | CLSPN isoform 1. | 0.950 |
| CDC7 | MCM10 | ENSPTRP00000069321 | ENSPTRP00000044662 | Cell division cycle 7 homolog. | Minichromosome maintenance complex component 10. | 0.968 |
| CDC7 | MCM2 | ENSPTRP00000069321 | ENSPTRP00000026448 | Cell division cycle 7 homolog. | DNA helicase; Belongs to the MCM family. | 0.982 |
| CDC7 | RPA1 | ENSPTRP00000069321 | ENSPTRP00000014573 | Cell division cycle 7 homolog. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.680 |
| CDC7 | TIMELESS | ENSPTRP00000069321 | ENSPTRP00000042163 | Cell division cycle 7 homolog. | Timeless circadian regulator. | 0.753 |
| CDC7 | TOPBP1 | ENSPTRP00000069321 | ENSPTRP00000026557 | Cell division cycle 7 homolog. | Topoisomerase (DNA) II binding protein 1. | 0.731 |
| CHEK1 | CDC45 | ENSPTRP00000067296 | ENSPTRP00000024215 | CHEK1 isoform 10. | CDC45 isoform 5. | 0.971 |
| CHEK1 | CDC7 | ENSPTRP00000067296 | ENSPTRP00000069321 | CHEK1 isoform 10. | Cell division cycle 7 homolog. | 0.900 |
