GDI1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000065454	GDI1	ENSPTRP00000065454	ENSPTRP00000047203	annotation not available	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	0.955
ENSPTRP00000065454	RAB12	ENSPTRP00000065454	ENSPTRP00000016773	annotation not available	RAB12, member RAS oncogene family.	0.745
ENSPTRP00000065454	RAB13	ENSPTRP00000065454	ENSPTRP00000002305	annotation not available	RAB13, member RAS oncogene family.	0.716
ENSPTRP00000065454	RAB1A	ENSPTRP00000065454	ENSPTRP00000020588	annotation not available	RAB1A, member RAS oncogene family.	0.874
ENSPTRP00000065454	RAB6A	ENSPTRP00000065454	ENSPTRP00000084267	annotation not available	RAB6A, member RAS oncogene family.	0.744
ENSPTRP00000065454	RAB8A	ENSPTRP00000065454	ENSPTRP00000018163	annotation not available	RAB8A, member RAS oncogene family.	0.827
ENSPTRP00000065454	RAB8B	ENSPTRP00000065454	ENSPTRP00000061884	annotation not available	RAB8B, member RAS oncogene family.	0.764
ENSPTRP00000065454	RAB9A	ENSPTRP00000065454	ENSPTRP00000037129	annotation not available	RAB9A isoform 1.	0.843
ENSPTRP00000088048	GDI1	ENSPTRP00000088048	ENSPTRP00000047203	annotation not available	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	0.955
ENSPTRP00000088048	RAB12	ENSPTRP00000088048	ENSPTRP00000016773	annotation not available	RAB12, member RAS oncogene family.	0.745
ENSPTRP00000088048	RAB13	ENSPTRP00000088048	ENSPTRP00000002305	annotation not available	RAB13, member RAS oncogene family.	0.716
ENSPTRP00000088048	RAB1A	ENSPTRP00000088048	ENSPTRP00000020588	annotation not available	RAB1A, member RAS oncogene family.	0.874
ENSPTRP00000088048	RAB6A	ENSPTRP00000088048	ENSPTRP00000084267	annotation not available	RAB6A, member RAS oncogene family.	0.744
ENSPTRP00000088048	RAB8A	ENSPTRP00000088048	ENSPTRP00000018163	annotation not available	RAB8A, member RAS oncogene family.	0.827
ENSPTRP00000088048	RAB8B	ENSPTRP00000088048	ENSPTRP00000061884	annotation not available	RAB8B, member RAS oncogene family.	0.764
ENSPTRP00000088048	RAB9A	ENSPTRP00000088048	ENSPTRP00000037129	annotation not available	RAB9A isoform 1.	0.843
GDI1	ENSPTRP00000065454	ENSPTRP00000047203	ENSPTRP00000065454	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	annotation not available	0.955
GDI1	ENSPTRP00000088048	ENSPTRP00000047203	ENSPTRP00000088048	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	annotation not available	0.955
GDI1	GDI2	ENSPTRP00000047203	ENSPTRP00000046835	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.993
GDI1	RAB12	ENSPTRP00000047203	ENSPTRP00000016773	Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes (By similarity).	RAB12, member RAS oncogene family.	0.890