STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (921 aa)    
Predicted Functional Partners:
LIN7A
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.997
APBA1
Amyloid beta precursor protein binding family A member 1.
   
 0.997
LIN7B
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.992
LIN7C
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.978
APBA2
Amyloid beta precursor protein binding family A member 2.
   
 0.973
APBA3
Amyloid beta precursor protein binding family A member 3.
   
0.970
GRIN1
Glutamate receptor, ionotropic, N-methyl D-aspartate 1.
   
 0.965
WHRN
WHRN isoform 2.
    
 0.961
EPS8
Epidermal growth factor receptor pathway substrate 8.
   
 0.951
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
   
0.938
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.