GIMAP1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASIP	GIMAP1	ENSPTRP00000022999	ENSPTRP00000047558	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).	GTPase IMAP family member 5.	0.783
ASIP	SPEF2	ENSPTRP00000022999	ENSPTRP00000066420	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).	SPEF2 isoform 4.	0.479
CD2	GIMAP1	ENSPTRP00000051908	ENSPTRP00000047558	CD2 isoform 1.	GTPase IMAP family member 5.	0.410
GIMAP1	ASIP	ENSPTRP00000047558	ENSPTRP00000022999	GTPase IMAP family member 5.	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).	0.783
GIMAP1	CD2	ENSPTRP00000047558	ENSPTRP00000051908	GTPase IMAP family member 5.	CD2 isoform 1.	0.410
GIMAP1	SPEF2	ENSPTRP00000047558	ENSPTRP00000066420	GTPase IMAP family member 5.	SPEF2 isoform 4.	0.462
GIMAP1	UNC79	ENSPTRP00000047558	ENSPTRP00000011362	GTPase IMAP family member 5.	UNC79 isoform 1.	0.574
GIMAP1	ZNF775	ENSPTRP00000047558	ENSPTRP00000047562	GTPase IMAP family member 5.	T0151199 isoform 1.	0.424
SPEF2	ASIP	ENSPTRP00000066420	ENSPTRP00000022999	SPEF2 isoform 4.	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).	0.479
SPEF2	GIMAP1	ENSPTRP00000066420	ENSPTRP00000047558	SPEF2 isoform 4.	GTPase IMAP family member 5.	0.462
UNC79	GIMAP1	ENSPTRP00000011362	ENSPTRP00000047558	UNC79 isoform 1.	GTPase IMAP family member 5.	0.574
ZNF775	GIMAP1	ENSPTRP00000047562	ENSPTRP00000047558	T0151199 isoform 1.	GTPase IMAP family member 5.	0.424