| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHID1 | SLC35B4 | ENSPTRP00000005545 | ENSPTRP00000047621 | Chitinase domain containing 1; Belongs to the glycosyl hydrolase 18 family. | Pleckstrin homology domain containing, family M, member 3. | 0.563 |
| CHID1 | SLC35D2 | ENSPTRP00000005545 | ENSPTRP00000036144 | Chitinase domain containing 1; Belongs to the glycosyl hydrolase 18 family. | Solute carrier family 35, member D2. | 0.554 |
| POFUT1 | POFUT2 | ENSPTRP00000022931 | ENSPTRP00000024102 | GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...] | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13. O-fucosylation of TSRs is also requir [...] | 0.961 |
| POFUT1 | SLC35B4 | ENSPTRP00000022931 | ENSPTRP00000047621 | GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...] | Pleckstrin homology domain containing, family M, member 3. | 0.559 |
| POFUT1 | SLC35C1 | ENSPTRP00000022931 | ENSPTRP00000006138 | GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...] | Solute carrier family 35, member C1. | 0.563 |
| POFUT1 | SLC35D1 | ENSPTRP00000022931 | ENSPTRP00000078933 | GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...] | Solute carrier family 35 member D1. | 0.495 |
| POFUT2 | POFUT1 | ENSPTRP00000024102 | ENSPTRP00000022931 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13. O-fucosylation of TSRs is also requir [...] | GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...] | 0.961 |
| POFUT2 | SLC35B4 | ENSPTRP00000024102 | ENSPTRP00000047621 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13. O-fucosylation of TSRs is also requir [...] | Pleckstrin homology domain containing, family M, member 3. | 0.601 |
| POFUT2 | SLC35C1 | ENSPTRP00000024102 | ENSPTRP00000006138 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13. O-fucosylation of TSRs is also requir [...] | Solute carrier family 35, member C1. | 0.465 |
| POFUT2 | SLC35C2 | ENSPTRP00000024102 | ENSPTRP00000066280 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13. O-fucosylation of TSRs is also requir [...] | Solute carrier family 35 member C2. | 0.536 |
| SLC35A5 | SLC35B4 | ENSPTRP00000026254 | ENSPTRP00000047621 | Solute carrier family 35, member A5. | Pleckstrin homology domain containing, family M, member 3. | 0.556 |
| SLC35A5 | SLC35C1 | ENSPTRP00000026254 | ENSPTRP00000006138 | Solute carrier family 35, member A5. | Solute carrier family 35, member C1. | 0.509 |
| SLC35A5 | SLC35C2 | ENSPTRP00000026254 | ENSPTRP00000066280 | Solute carrier family 35, member A5. | Solute carrier family 35 member C2. | 0.598 |
| SLC35A5 | SLC35D1 | ENSPTRP00000026254 | ENSPTRP00000078933 | Solute carrier family 35, member A5. | Solute carrier family 35 member D1. | 0.509 |
| SLC35A5 | SLC35D2 | ENSPTRP00000026254 | ENSPTRP00000036144 | Solute carrier family 35, member A5. | Solute carrier family 35, member D2. | 0.413 |
| SLC35A5 | SLC35D3 | ENSPTRP00000026254 | ENSPTRP00000031820 | Solute carrier family 35, member A5. | Solute carrier family 35 member D3. | 0.579 |
| SLC35A5 | SLC35E1 | ENSPTRP00000026254 | ENSPTRP00000039053 | Solute carrier family 35, member A5. | Solute carrier family 35, member E1. | 0.464 |
| SLC35B4 | CHID1 | ENSPTRP00000047621 | ENSPTRP00000005545 | Pleckstrin homology domain containing, family M, member 3. | Chitinase domain containing 1; Belongs to the glycosyl hydrolase 18 family. | 0.563 |
| SLC35B4 | POFUT1 | ENSPTRP00000047621 | ENSPTRP00000022931 | Pleckstrin homology domain containing, family M, member 3. | GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...] | 0.559 |
| SLC35B4 | POFUT2 | ENSPTRP00000047621 | ENSPTRP00000024102 | Pleckstrin homology domain containing, family M, member 3. | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13. O-fucosylation of TSRs is also requir [...] | 0.601 |
