| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAPN1 | CAPN2 | ENSPTRP00000067819 | ENSPTRP00000091012 | Calpain 1, (Mu/I) large subunit; Belongs to the peptidase C2 family. | Calpain 2, (M/II) large subunit; Belongs to the peptidase C2 family. | 0.979 |
| CAPN1 | CASP12 | ENSPTRP00000067819 | ENSPTRP00000047678 | Calpain 1, (Mu/I) large subunit; Belongs to the peptidase C2 family. | CASP12 isoform 1; Belongs to the peptidase C14A family. | 0.915 |
| CAPN1 | CASP3 | ENSPTRP00000067819 | ENSPTRP00000054330 | Calpain 1, (Mu/I) large subunit; Belongs to the peptidase C2 family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.506 |
| CAPN2 | CAPN1 | ENSPTRP00000091012 | ENSPTRP00000067819 | Calpain 2, (M/II) large subunit; Belongs to the peptidase C2 family. | Calpain 1, (Mu/I) large subunit; Belongs to the peptidase C2 family. | 0.979 |
| CAPN2 | CASP12 | ENSPTRP00000091012 | ENSPTRP00000047678 | Calpain 2, (M/II) large subunit; Belongs to the peptidase C2 family. | CASP12 isoform 1; Belongs to the peptidase C14A family. | 0.910 |
| CASP1 | CASP12 | ENSPTRP00000078835 | ENSPTRP00000047678 | CASP1 isoform 4; Belongs to the peptidase C14A family. | CASP12 isoform 1; Belongs to the peptidase C14A family. | 0.903 |
| CASP1 | CASP3 | ENSPTRP00000078835 | ENSPTRP00000054330 | CASP1 isoform 4; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.930 |
| CASP1 | CASP4 | ENSPTRP00000078835 | ENSPTRP00000041705 | CASP1 isoform 4; Belongs to the peptidase C14A family. | Caspase 4, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.797 |
| CASP1 | CASP5 | ENSPTRP00000078835 | ENSPTRP00000007279 | CASP1 isoform 4; Belongs to the peptidase C14A family. | CASP5 isoform 3; Belongs to the peptidase C14A family. | 0.784 |
| CASP1 | CASP7 | ENSPTRP00000078835 | ENSPTRP00000074501 | CASP1 isoform 4; Belongs to the peptidase C14A family. | CASP7 isoform 1; Belongs to the peptidase C14A family. | 0.929 |
| CASP1 | GSDMD | ENSPTRP00000078835 | ENSPTRP00000035317 | CASP1 isoform 4; Belongs to the peptidase C14A family. | GSDMD isoform 4. | 0.996 |
| CASP1 | PYCARD | ENSPTRP00000078835 | ENSPTRP00000013732 | CASP1 isoform 4; Belongs to the peptidase C14A family. | PYD and CARD domain containing. | 0.999 |
| CASP12 | CAPN1 | ENSPTRP00000047678 | ENSPTRP00000067819 | CASP12 isoform 1; Belongs to the peptidase C14A family. | Calpain 1, (Mu/I) large subunit; Belongs to the peptidase C2 family. | 0.915 |
| CASP12 | CAPN2 | ENSPTRP00000047678 | ENSPTRP00000091012 | CASP12 isoform 1; Belongs to the peptidase C14A family. | Calpain 2, (M/II) large subunit; Belongs to the peptidase C2 family. | 0.910 |
| CASP12 | CASP1 | ENSPTRP00000047678 | ENSPTRP00000078835 | CASP12 isoform 1; Belongs to the peptidase C14A family. | CASP1 isoform 4; Belongs to the peptidase C14A family. | 0.903 |
| CASP12 | CASP3 | ENSPTRP00000047678 | ENSPTRP00000054330 | CASP12 isoform 1; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.925 |
| CASP12 | CASP4 | ENSPTRP00000047678 | ENSPTRP00000041705 | CASP12 isoform 1; Belongs to the peptidase C14A family. | Caspase 4, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.927 |
| CASP12 | CASP5 | ENSPTRP00000047678 | ENSPTRP00000007279 | CASP12 isoform 1; Belongs to the peptidase C14A family. | CASP5 isoform 3; Belongs to the peptidase C14A family. | 0.927 |
| CASP12 | CASP7 | ENSPTRP00000047678 | ENSPTRP00000074501 | CASP12 isoform 1; Belongs to the peptidase C14A family. | CASP7 isoform 1; Belongs to the peptidase C14A family. | 0.918 |
| CASP12 | GSDMD | ENSPTRP00000047678 | ENSPTRP00000035317 | CASP12 isoform 1; Belongs to the peptidase C14A family. | GSDMD isoform 4. | 0.863 |
