| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABCG5 | APOB | ENSPTRP00000020391 | ENSPTRP00000052150 | ATP binding cassette subfamily G member 5. | APOB isoform 1. | 0.599 |
| ABCG5 | NPC1L1 | ENSPTRP00000020391 | ENSPTRP00000048020 | ATP binding cassette subfamily G member 5. | NPC1 like intracellular cholesterol transporter 1. | 0.761 |
| ABCG5 | SCARB1 | ENSPTRP00000020391 | ENSPTRP00000079498 | ATP binding cassette subfamily G member 5. | SCARB1 isoform 8; Belongs to the CD36 family. | 0.495 |
| ABCG5 | SREBF1 | ENSPTRP00000020391 | ENSPTRP00000076133 | ATP binding cassette subfamily G member 5. | SREBF1 isoform 6. | 0.546 |
| ABCG5 | SREBF2 | ENSPTRP00000020391 | ENSPTRP00000024869 | ATP binding cassette subfamily G member 5. | Sterol regulatory element binding transcription factor 2. | 0.696 |
| APOB | ABCG5 | ENSPTRP00000052150 | ENSPTRP00000020391 | APOB isoform 1. | ATP binding cassette subfamily G member 5. | 0.599 |
| APOB | CD81 | ENSPTRP00000052150 | ENSPTRP00000074537 | APOB isoform 1. | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | 0.596 |
| APOB | CLDN1 | ENSPTRP00000052150 | ENSPTRP00000027073 | APOB isoform 1. | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. | 0.520 |
| APOB | EGFR | ENSPTRP00000052150 | ENSPTRP00000069741 | APOB isoform 1. | Receptor protein-tyrosine kinase. | 0.631 |
| APOB | EPHA2 | ENSPTRP00000052150 | ENSPTRP00000000400 | APOB isoform 1. | EPH receptor A2. | 0.409 |
| APOB | NPC1L1 | ENSPTRP00000052150 | ENSPTRP00000048020 | APOB isoform 1. | NPC1 like intracellular cholesterol transporter 1. | 0.713 |
| APOB | NPC2 | ENSPTRP00000052150 | ENSPTRP00000011092 | APOB isoform 1. | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | 0.559 |
| APOB | SCARB1 | ENSPTRP00000052150 | ENSPTRP00000079498 | APOB isoform 1. | SCARB1 isoform 8; Belongs to the CD36 family. | 0.929 |
| APOB | SREBF1 | ENSPTRP00000052150 | ENSPTRP00000076133 | APOB isoform 1. | SREBF1 isoform 6. | 0.495 |
| APOB | SREBF2 | ENSPTRP00000052150 | ENSPTRP00000024869 | APOB isoform 1. | Sterol regulatory element binding transcription factor 2. | 0.429 |
| CD81 | APOB | ENSPTRP00000074537 | ENSPTRP00000052150 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | APOB isoform 1. | 0.596 |
| CD81 | CLDN1 | ENSPTRP00000074537 | ENSPTRP00000027073 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. | 0.814 |
| CD81 | EGFR | ENSPTRP00000074537 | ENSPTRP00000069741 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Receptor protein-tyrosine kinase. | 0.685 |
| CD81 | EPHA2 | ENSPTRP00000074537 | ENSPTRP00000000400 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | EPH receptor A2. | 0.786 |
| CD81 | NPC1L1 | ENSPTRP00000074537 | ENSPTRP00000048020 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | NPC1 like intracellular cholesterol transporter 1. | 0.819 |
