CD5 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCR7	CD19	ENSPTRP00000053043	ENSPTRP00000079367	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD19 isoform 1.	0.875
CCR7	CD2	ENSPTRP00000053043	ENSPTRP00000051908	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD2 isoform 1.	0.514
CCR7	CD3E	ENSPTRP00000053043	ENSPTRP00000007441	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD3E isoform 2.	0.607
CCR7	CD4	ENSPTRP00000053043	ENSPTRP00000054833	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.962
CCR7	CD5	ENSPTRP00000053043	ENSPTRP00000048059	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD5 isoform 1.	0.910
CCR7	FOXP3	ENSPTRP00000053043	ENSPTRP00000037587	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	FOXP3 isoform 4.	0.810
CD19	CCR7	ENSPTRP00000079367	ENSPTRP00000053043	CD19 isoform 1.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.875
CD19	CD2	ENSPTRP00000079367	ENSPTRP00000051908	CD19 isoform 1.	CD2 isoform 1.	0.609
CD19	CD3E	ENSPTRP00000079367	ENSPTRP00000007441	CD19 isoform 1.	CD3E isoform 2.	0.655
CD19	CD4	ENSPTRP00000079367	ENSPTRP00000054833	CD19 isoform 1.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.953
CD19	CD5	ENSPTRP00000079367	ENSPTRP00000048059	CD19 isoform 1.	CD5 isoform 1.	0.764
CD19	CD7	ENSPTRP00000079367	ENSPTRP00000052644	CD19 isoform 1.	CD7 isoform 1.	0.622
CD19	FOXP3	ENSPTRP00000079367	ENSPTRP00000037587	CD19 isoform 1.	FOXP3 isoform 4.	0.759
CD19	LCK	ENSPTRP00000079367	ENSPTRP00000000842	CD19 isoform 1.	Tyrosine-protein kinase.	0.590
CD19	ZAP70	ENSPTRP00000079367	ENSPTRP00000021008	CD19 isoform 1.	Tyrosine-protein kinase.	0.494
CD2	CCR7	ENSPTRP00000051908	ENSPTRP00000053043	CD2 isoform 1.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.514
CD2	CD19	ENSPTRP00000051908	ENSPTRP00000079367	CD2 isoform 1.	CD19 isoform 1.	0.609
CD2	CD3E	ENSPTRP00000051908	ENSPTRP00000007441	CD2 isoform 1.	CD3E isoform 2.	0.944
CD2	CD4	ENSPTRP00000051908	ENSPTRP00000054833	CD2 isoform 1.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.844
CD2	CD5	ENSPTRP00000051908	ENSPTRP00000048059	CD2 isoform 1.	CD5 isoform 1.	0.879