STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAX1BP1Tax1 binding protein 1. (813 aa)    
Predicted Functional Partners:
TNFAIP3
Tumor necrosis factor, alpha-induced protein 3.
    
 0.985
RNF11
Ring finger protein 11.
   
 
 0.866
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.848
AZI2
5-azacytidine induced 2.
    
 
 0.838
MYO6
MYO6 isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.814
UBC
Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]
   
 0.773
TBK1
TANK-binding kinase 1.
    
 0.720
LGALS8
Galectin.
   
 
 0.705
OPTN
OPTN isoform 1.
   
 0.695
BIRC2
Baculoviral IAP repeat containing 2.
   
 0.690
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.